Dovitinib (TKI-258, CHIR-258)

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Names

[ CAS No. ]:
405169-16-6

[ Name ]:
Dovitinib (TKI-258, CHIR-258)

[Synonym ]:
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
2(1H)-Quinolinone, 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
Dovitinib
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
4-Amino-5-fluor-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]chinolin-2(1H)-on
Dovitinib (TKI-258,CHIR-258)
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one
Unii-I35H55G906
Dovitinib (TKI-258, CHIR-258)
CHIR-258
4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one
4-amino-5-fluoro-3-[6-(4-methyl-piperazin-1-yl)-1H-benzoimidazol-2-yl]-1H-quinolin-2-one
4-Amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one
TKI-258
CHIR-258(Dovitinib,TKI258)
Dovitinib (TKI-258)
CHIR258 7.7G
CHIR-258(Dovitinib)

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C21H21FN6O

[ Molecular Weight ]:
392.429

[ Exact Mass ]:
392.176086

[ PSA ]:
94.04000

[ LogP ]:
1.59

[ Index of Refraction ]:
1.691

[ Storage condition ]:
-20°C

Precursor & DownStream

Precursor

  • Ethyl 2-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)acetate
  • 2-Amino-6-fluorobenzonitrile
  • methylpiperazine
  • 5-Chloro-2-nitroaniline
  • 5-(4-Methylpiperazin-1-yl)-2-nitroaniline
  • 4-(4-Methylpiperazino)-1,2-benzenediamine

DownStream

Related Compounds

  • Dovitinib (TKI-258) Dilactic Acid
  • Dovitinib lactate
  • Dovitinib-d8
  • Dovitinib Lactate
  • (1R-cis)-1-(2,2,6-trimethylcyclohexyl)ethanone
  • Tromantadine
  • N-{[1-(pyridin-4-yl)cyclohexyl]methyl}prop-2-enamide
  • 4-[4-(Prop-2-ynoyl)piperazin-1-yl]benzene-1-sulfonamide
  • 4-[4-(Dimethylamino)but-2-enoyl]-3-(4-fluoro-2-methylphenyl)piperazin-2-one
  • tert-butyl N-methyl-N-(1-{[4-phenyl-1-(prop-2-enoyl)piperidin-4-yl]formamido}propan-2-yl)carbamate
  • N-[3-(2-fluorophenyl)-1H-1,2,4-triazol-5-yl]prop-2-enamide
  • N-{2-[(6-fluoro-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl)carbamoyl]ethyl}prop-2-enamide
  • N-[4-chloro-3-(pyrrolidine-1-sulfonyl)phenyl]-1-(prop-2-enoyl)piperidine-4-carboxamide
  • tert-butyl 2-{[(2E)-4-(dimethylamino)but-2-enamido]methyl}-hexahydro-1H-furo[3,4-b]pyrrole-1-carboxylate
  • N-(1-cyclopropylethyl)-N-ethyl-4-(prop-2-enamido)benzamide
  • N-[(2,2-dimethylcyclopropyl)methyl]-N-methyl-4-(prop-2-enamido)benzamide
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