Dovitinib (TKI-258, CHIR-258)

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Names

[ CAS No. ]:
405169-16-6

[ Name ]:
Dovitinib (TKI-258, CHIR-258)

[Synonym ]:
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
2(1H)-Quinolinone, 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
Dovitinib
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
4-Amino-5-fluor-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]chinolin-2(1H)-on
Dovitinib (TKI-258,CHIR-258)
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one
Unii-I35H55G906
Dovitinib (TKI-258, CHIR-258)
CHIR-258
4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one
4-amino-5-fluoro-3-[6-(4-methyl-piperazin-1-yl)-1H-benzoimidazol-2-yl]-1H-quinolin-2-one
4-Amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one
TKI-258
CHIR-258(Dovitinib,TKI258)
Dovitinib (TKI-258)
CHIR258 7.7G
CHIR-258(Dovitinib)

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C21H21FN6O

[ Molecular Weight ]:
392.429

[ Exact Mass ]:
392.176086

[ PSA ]:
94.04000

[ LogP ]:
1.59

[ Index of Refraction ]:
1.691

[ Storage condition ]:
-20°C

Precursor & DownStream

Precursor

  • Ethyl 2-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)acetate
  • 2-Amino-6-fluorobenzonitrile
  • methylpiperazine
  • 5-Chloro-2-nitroaniline
  • 5-(4-Methylpiperazin-1-yl)-2-nitroaniline
  • 4-(4-Methylpiperazino)-1,2-benzenediamine

DownStream

Related Compounds

  • Dovitinib (TKI-258) Dilactic Acid
  • Dovitinib lactate
  • Dovitinib-d8
  • Dovitinib Lactate
  • (1R-cis)-1-(2,2,6-trimethylcyclohexyl)ethanone
  • Tromantadine
  • rac-methyl (1R,2R)-2-{[(benzyloxy)carbonyl]amino}-1-hydroxycyclopentane-1-carboxylate
  • Methyl 1-({[(benzyloxy)carbonyl]amino}methyl)-3-hydroxycyclobutane-1-carboxylate
  • (2S,3R)-2-{benzyl[(prop-2-en-1-yloxy)carbonyl]amino}-3-hydroxybutanoic acid
  • (4-Chloro-2-ethoxy-3-fluorophenyl)methanol
  • Threonine, N-benzoyl-, methyl ester, 4-methylbenzenesulfonate (ester)
  • 2-[({1-[(Tert-butoxy)carbonyl]-1,2,3,4-tetrahydroquinolin-8-yl}oxy)methyl]furan-3-carboxylic acid
  • tert-butyl N-butyl-N-(4-nitro-2-sulfamoylphenyl)carbamate
  • (9H-fluoren-9-yl)methyl 3-(methanesulfonyloxy)azetidine-1-carboxylate
  • benzyl N-{[(2S,4S)-1-[2-(dimethylamino)pyrimidin-4-yl]-4-fluoropyrrolidin-2-yl]methyl}carbamate
  • Benzyl 4-(naphthalene-1-carbonyl)piperidine-1-carboxylate
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