1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

Names

[ CAS No. ]:
40733-26-4

[ Name ]:
1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

[Synonym ]:
MFCD01631042

Chemical & Physical Properties

[ Molecular Formula ]:
C22H42N2O5Si2

[ Molecular Weight ]:
470.75000

[ Exact Mass ]:
470.26300

[ PSA ]:
82.55000

[ LogP ]:
4.54470

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-Butyldimethylsilyl chloride
  • Thymidine
  • Phenylboronic acid
  • 4-Methoxyphenylboronic acid
  • 2-Naphthaleneboronic acid
  • 1-Naphthaleneboronic acid
  • 4-Boronoanisole
  • 4-Acetylphenylboronic acid
  • 4-(Methylthio)phenylboronic acid

DownStream

  • 5-Hydroxymethyl-2'-deoxyuridine
  • Thymidine
  • tert-butyl-dimethyl-phenylmethoxysilane
  • Thymine
  • 1,4-ANHYDRO-2-DEOXY-3,5-BIS-O-(T-BUTYLDIMETHYLSILYL)-D-ERYTHRO-PENT-1-ENITOL
  • 5'-o-(dimethoxytrityl)-2'-o-methyl-5-methyluridine
  • 3',5'-bis-o-(t-butyldimethylsilyl)-o4-(2,4,6-triisopropyl-phenylsulfonyl)thymidine
  • 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-phenethyl-pyrimidine-2,4-dione