H-Tyr-OEt·HCl

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Names

[ CAS No. ]:
4089-07-0

[ Name ]:
H-Tyr-OEt·HCl

[Synonym ]:
L-Tyrosine Ethyl Ester Hydrochloride
Ethyl L-tyrosinate hydrochloride (1:1)
Tyrosine, ethyl ester, hydrochloride, L-
tyrosineethylesterhydrochloride
Tyr-Oet Hcl
EthylL-tyrosinatehydrochloride
EINECS 223-820-2
L-Tyrosine ethyl est
H-Tyr-OEt HCl
L-Tyr-OEt.HCL
TEE
L-Tyrosine, ethyl ester, hydrochloride (1:1)
H-Tyr-OEt·HCl
MFCD00063047
L-Tyrosine, ethyl ester, hydrochloride
L-TYROSINE ETHYL ESTER HCL
H-L-Tyr-OEt*HCl
H-Tyr-Oet.Hcl
L-tyrosine ethyl ester monohydrochloride
DL-tyrosine ethyl ester hydrochloride
TYROSINE-OET HCL

Chemical & Physical Properties

[ Density]:
1.177 g/cm3

[ Boiling Point ]:
343.3ºC at 760 mmHg

[ Melting Point ]:
166-170 °C

[ Molecular Formula ]:
C11H16ClNO3

[ Molecular Weight ]:
245.703

[ Flash Point ]:
161.4ºC

[ Exact Mass ]:
245.081863

[ PSA ]:
72.55000

[ LogP ]:
2.32740

[ Index of Refraction ]:
-6.5 ° (C=2, H2O)

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YP2580000
CHEMICAL NAME :
Tyrosine, ethyl ester, hydrochloride, L-
CAS REGISTRY NUMBER :
4089-07-0
LAST UPDATED :
198903
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H15-N-O3.Cl-H
MOLECULAR WEIGHT :
245.73

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 18,474,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7710 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 18,474,1987

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
YP2580000

[ Packaging Group ]:
III

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethanol
  • L-Tyrosine
  • Methyl tert-butyl ether

DownStream

  • Bz-Tyr-OEt; BTEE
  • Ethyl L-tyrosinate
  • tyrosinol
  • Boc-Tyr-Oet
  • L-Tyrosine
  • o-phospho-l-tyrosine
  • H-Gly-Tyr-OH
  • z-tyr-oh
  • ethyl 3-(4-hydroxyphenyl)-2-[(2-phenylmethoxycarbonylaminoacetyl)amino]propanoate
  • L-Tyrosine,N-[N,S-bis(triphenylmethyl)-L-cysteinyl]-, ethyl ester (9CI)

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Transverse dephasing optimised NMR spectroscopy in solids: natural-abundance 13C correlation spectra.

ChemPhysChem 5(6) , 869-75, (2004)

Dimerisation of N-acetyl-L-tyrosine ethyl ester and Abeta peptides via formation of dityrosine.

Free Radic. Res. 40 , 1-9, (2006)

Alzheimer's disease (AD) is characterised by the formation of amyloid deposits composed primarily of the amyloid beta-peptide (Abeta). This peptide has been shown to bind redox active metals ions such...

Dimorphism of the prodrug L-tyrosine ethyl ester: pressure-temperature state diagram and crystal structure of phase II.

J. Pharm. Sci. 100 , 4774-4782, (2011)

Polymorphism is important in the field of solid-state behavior of drug molecules because of the continuous drive for complete control over drug properties. By comparing different structures of a serie...


More Articles

Related Compounds

  • H-Tyr-Oet·HCl
  • H-TYR-GLY-TRP-OH
  • H-Tyr-Tic-Phe-Asp-Val-Val-Gly-NH2
  • H-Tyr-Ser-Pro-Thr-Ser-Pro-Ser-Tyr-OH
  • H-Tyr(Tos)-OH
  • H-Tyr-D-Arg-Phe-Gly-Tyr-Pro-NH2
  • N-[2-(tetrahydrofuran-2-yl)-1H-benzimidazol-5-yl]thiophene-2-sulfonamide
  • 4-chloro-N-[2-(tetrahydrofuran-2-yl)-1H-benzimidazol-5-yl]benzenesulfonamide
  • 4-(1H-indol-3-yl)-N-[2-(pyridin-2-yl)ethyl]butanamide
  • 3-[2-Amino-2-(1,3-benzothiazol-2-yl)ethyl]benzonitrile
  • 3-Bromo-6-(piperidin-1-yl)pyridazine
  • 1-[(Furan-2-yl)methyl]-1,4-diazepane
  • I+/--(3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)-3-piperidinemethanol
  • Thr-Met-Leu-Ala-Arg-Leu-Ala-Ser-Ala
  • Leu-Thr-Phe-Gly-Asp-Val-Val-Ala-Val
  • Ala-Met-Thr-Gln-Leu-Leu-Ala-Gly-Val
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