S-(2-Aminoethyl)-L-cysteine hydrochloride

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Names

[ CAS No. ]:
4099-35-8

[ Name ]:
S-(2-Aminoethyl)-L-cysteine hydrochloride

[Synonym ]:
H-Cys(aminoethyl)-OH
H-CYS(ET-NH2)-OH HCL
S-(2-aminoethyl)-L-cysteine monohydrochloride
CYSTEINE(AMINOETHYL)-OH HCL
L-4-thialysine hydrochloride
MFCD00036385
usafxr-43
EINECS 223-862-1
S-(2-Amino-aethyl)-L-cystein,Hydrochlorid
S-(aminoethyl)-L-cysteine hydrochloride
thialysinehydrochloride
S-(2-amino-ethyl)-L-cysteine,hydrochloride
lj226
L-Thialysin Hydrochlorid
H-CYS(AMINOETHYL)-OH HCL
THIALSINE

Chemical & Physical Properties

[ Density]:
1.289g/cm3

[ Boiling Point ]:
341.1ºC at 760 mmHg

[ Molecular Formula ]:
C5H13ClN2O2S

[ Molecular Weight ]:
200.68700

[ Flash Point ]:
160.1ºC

[ Exact Mass ]:
200.03900

[ PSA ]:
114.64000

[ LogP ]:
1.29280

[ Index of Refraction ]:
1.57

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA1690000
CHEMICAL NAME :
Cysteine, S-(2-aminoethyl)-, monohydrochloride, L-
CAS REGISTRY NUMBER :
4099-35-8
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H12-N2-O2-S.Cl-H
MOLECULAR WEIGHT :
200.71
WISWESSER LINE NOTATION :
Z2S1YZVQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2155776
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
HA1690000

[ HS Code ]:
2930909090

Synthetic Route

Precursor & DownStream

Precursor

  • Cysteamine Hydrochloride
  • (S)-3-amino-2-oxetanone trifluoroacetic acid salt

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Evidence for conformational movement and radical mechanism in the reaction of 4-thia-L-lysine with lysine 5,6-aminomutase.

J. Phys. Chem. B 113(36) , 12161-3, (2009)

We demonstrate that the steady state reaction of lysine 5,6-aminomutase with substrate analogue 4-thia-l-lysine generates a radical intermediate, which accumulates in the enzyme to an electron paramag...

Radical triplets and suicide inhibition in reactions of 4-thia-D- and 4-thia-L-lysine with lysine 5,6-aminomutase.

Biochemistry 48(34) , 8151-60, (2009)

Lysine 5,6-aminomutase (5,6-LAM) catalyzes the interconversions of D- or L-lysine and the corresponding enantiomers of 2,5-diaminohexanoate, as well as the interconversion of L-beta-lysine and l-3,5-d...

Inhibition of lysine 2,3-aminomutase by the alternative substrate 4-thialysine and characterization of the 4-thialysyl radical intermediate.

Arch. Biochem. Biophys. 387(2) , 281-8, (2001)

Lysine 2,3-aminomutase catalyzes the interconversion of L-lysine and L-beta-lysine. 4-Thia-L-lysine (4-thialysine) is an alternative substrate for Lysine 2,3-aminomutase. The organic free radical that...


More Articles


Related Compounds

  • S-(2-Aminoethyl)-L-cysteine hydrochloride
  • 2-Butoxypropanoic acid
  • (2R)-2-amino-3-(2-aminoethylsulfanyl)propanoic acid,hydrochloride
  • Di-Fmoc-S-(2-aminoethyl)-L-cysteine
  • S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride
  • Cysteine, S-(2-aminoethyl)- (9CI)