((3aR,4R,6R,6aR)-6-Methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol

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Names

[ CAS No. ]:
4099-85-8

[ Name ]:
((3aR,4R,6R,6aR)-6-Methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol

[Synonym ]:
MFCD00038805
((3aR,4R,6R,6aR)-6-Methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol
Methyl-2,3-O-isopropylidene-β-D-ribofuranoside
EINECS 223-865-8
β-D-Ribofuranoside, methyl 2,3-O-(1-methylethylidene)-
Methyl 2,3-O-isopropylidene-β-D-ribofuranoside
Methyl 2,3-o-isopropylidene-beta-D-ribofuranoside

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
287.3±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H16O5

[ Molecular Weight ]:
204.220

[ Flash Point ]:
127.5±27.3 °C

[ Exact Mass ]:
204.099777

[ PSA ]:
57.15000

[ LogP ]:
0.55

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.492

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
MISCIBLE

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S37/39

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • D-Ribose
  • 2,2-Dimethoxypropane
  • Acetone
  • Methanol
  • 2,3-O-isopropylidine-D-ribose
  • beta-D-Ribofuranose (9CI)
  • methyl 5-(4-methoxybenzyloxy)-2,3-O-isopropylidene-β-D-ribofuranoside
  • Methyl 2,3-O-Isopropylidene-5-O-benzyl-β-D-ribofuranoside
  • (3aR,4S,6R,6aR)-tetrahydro-6-methoxy-2,2-dimethylfuro-[3,4-d][1,3]dioxole-4-carbaldehyde

DownStream

  • Methyl 2,3-O-Isopropylidene-5-O-benzyl-β-D-ribofuranoside
  • 2,3-O-ISOPROPYLIDENE-1-O-METHYL-D-RIBOSIC ACID
  • Ribavirin
  • b-D-Ribofuranoside, methyl5-deoxy-5-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2,3-O-(1-methylethylidene)-
  • Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside
  • Ticagrelor
  • (2S,3R,4R,5R)-5-METHYLTETRAHYDROFURAN-2,3,4-TRIYL TRIACETATE
  • Ticagrelor InterMediate1
  • Methyl-5-deoxy-2,3-O-isopropylidene-D-ribofuranoside
  • N-[(3aS,4R,6S,6aR)-Tetrahydro-6-hydroxy-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]carbamicacid phenylmethyl ester

Related Compounds

  • 2-amino-4-(2-methylpropyl)-1H-pyrrole-3-carboxylic acid
  • tert-butyl N-(4-butyl-2-cyanophenyl)carbamate
  • 3-Methoxy-1,2-thiazole-4-sulfonamide
  • Benzyl 3-ethyl-3-(hydroxymethyl)morpholine-4-carboxylate
  • benzyl N-{[1-(2-hydroxyethoxy)cyclobutyl]methyl}carbamate
  • benzyl N-(2,2-dimethylpropyl)-N-(1-hydroxypropan-2-yl)carbamate
  • tert-butyl N-(4-chlorophthalazin-1-yl)carbamate
  • Phenol, 4-[2-(6-bromo-3-methyl-2,4-dinitrophenyl)diazenyl]-2-methyl-, 1-acetate
  • 2-{[1-(Ethanesulfonyl)piperidin-4-yl]amino}acetic acid
  • rac-[(1R,2R)-2-(2-chloro-1,3-thiazol-5-yl)cyclopropyl]methanamine
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