ENPROFYLLINE

Suppliers

Names

[ CAS No. ]:
41078-02-8

[ Name ]:
ENPROFYLLINE

[Synonym ]:
3,7-dihydro-3-propyl-1H-purine-2,6-dione
enprophylline
3-propylxanthine
Enprofilina [INN-Spanish]
EINECS 255-201-8
3-propyl-7H-purine-2,6-dione
Enprofilina
Nilyph
Oxeze
Enprofyllinum [INN-Latin]
Enprofyllinum
3-propylxanthine (PX)
MFCD00043205
3-n-propylxanthine

Chemical & Physical Properties

[ Density]:
1.367 g/cm3

[ Molecular Formula ]:
C8H10N4O2

[ Molecular Weight ]:
194.19100

[ Exact Mass ]:
194.08000

[ PSA ]:
83.54000

[ Index of Refraction ]:
1.583

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UO8439700
CHEMICAL NAME :
1H-Purine-2,6-dione, 3,7-dihydro-3-propyl-
CAS REGISTRY NUMBER :
41078-02-8
LAST UPDATED :
199606
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H10-N4-O2
MOLECULAR WEIGHT :
194.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
481 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 22(Suppl 2),125,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
254 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 22(Suppl 2),125,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
157 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,313,1981

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
36

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Diethoxymethyl acetate
  • 5,6-diamino 1-n-propyl-1,3-dihydropyrimidine-2,4-dione
  • 6-amino-5-nitroso-1-propylpyrimidine-2,4(1H,3H)-dione
  • 6-Amino-1-propylpyrimidine-2,4(1H,3H)-dione

DownStream

  • 1,3-DIPROPYL-1H-PURINE-2,6(3H,7H)-DIONE
  • 1,3-Dipropyl-7-methylxanthine
  • 3,7-dipropylpurine-2,6-dione
  • 1-methyl-3,7-dipropylpurine-2,6-dione
  • 1H-Purine-2,6-dione,3,7-dihydro-1,7-dimethyl-3-propyl-

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 6-chloro-4-(4-fluoro-2-methylphenyl)-3-Pyridinamine hydrobromide
  • 6-Ethyl-3-(1,2,3,6-tetrahydro-1-methyl-4-pyridinyl)-1H-pyrrolo[2,3-b]pyridine
  • 6-Phenyl-4-(trifluoromethyl)-2,3-pyridinediamine
  • 7-(Benzyloxy)-3-chloro-6-iodoquinoline
  • 7-(Cyclopropyloxy)-6-[(1,1-dimethylethyl)sulfonyl]-3-iodoimidazo[1,2-a]pyridine
  • 7-(Cyclopropyloxy)-6-[(1,1-dimethylethyl)sulfonyl]imidazo[1,2-a]pyridine
  • 7-(Tert-butoxycarbonyl)-4-methoxy-5,6,7,8-tetrahydro-1,7-naphthyridine-2-carboxylate
  • 7-amino-1-benzyl-1,2-dihydro-3H-indazol-3-one
  • 7-Bromo-1,2,3,4-tetrahydro-5-methyl-2-(tetrahydro-2H-pyran-4-yl)isoquinoline
  • 7-Chloro-3-(4-methoxyphenyl)-5-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.