7-Methoxy-3,4-dihydronaphthalen-2(1H)-one

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Names

[ CAS No. ]:
4133-34-0

[ Name ]:
7-Methoxy-3,4-dihydronaphthalen-2(1H)-one

[Synonym ]:
3,4-Dihydro-7-methoxy-2(1H)-naphthalenone
3,4-dihydro-7-methoxynaphthalen-1(2H)-one
7-Methoxy-3,4-dihydronaphthalen-1(2H)-one
EINECS 223-954-1
MFCD00001730
7-Methoxy-2-tetralone
1(2H)-Naphthalenone, 3,4-dihydro-7-methoxy-
2(1H)-Naphthalenone, 3,4-dihydro-7-methoxy-
7-methoxy-3,4-dihydro-1H-naphthalen-2-one
7-Methoxy-3,4-dihydro-2(1H)-naphthalenone
7-Methoxy-3,4-dihydronaphthalen-2(1H)-one
7-Methoxy-3,4-dihydro-1(2H)-naphthalenone

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
306.8±0.0 °C at 760 mmHg

[ Melting Point ]:
27 - 28ºC

[ Molecular Formula ]:
C11H12O2

[ Molecular Weight ]:
176.212

[ Flash Point ]:
150.8±21.4 °C

[ Exact Mass ]:
176.083725

[ PSA ]:
26.30000

[ LogP ]:
1.64

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.549

[ Storage condition ]:
0-6°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xn, Xi

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914509090

Synthetic Route

Precursor & DownStream

Precursor

  • 7-methoxy-3,4-dihydronaphthalen-2(1H)-one sodium hydrogencarbonate
  • 1,1-diethoxy-4-(4-methoxyphenyl)butan-2-ol
  • 6-METHOXY-1A,2,3,7B-TETRAHYDRO-1-OXA-CYCLOPROPA[A]NAPHTHALENE
  • Diethyl ether
  • 2,7-Dimethoxynaphthalene
  • tert-butyl((4-(4-methoxyphenyl)but-1-en-2-yl)oxy)dimethylsilane
  • (1S,2R)-7-methoxy-1,2,3,4-tetrahydronaphthalene-1,2-diol
  • 7-Methoxy-1-tetralone
  • 4-Methoxybenzaldehyde

DownStream

  • 7-Hydroxy-2-tetralone
  • 1-benzyl-7-methoxy-3,4-dihydro-1H-naphthalen-2-one
  • 1-Allyl-7-Methoxy-2-tetralone
  • (S)-2-Amino-7-hydroxytetralin
  • 7-HYDROXY-NAPHTHALENE-2-CARBONITRILE
  • (R)-(+)-7-METHOXY 2-AMINOTETRALIN
  • (S)-2-Amino-1,2,3,4-tetrahydro-7-methoxynaphthalene
  • 2-amino-7-methoxy-3,4-dihydro-1H-naphthalene-2-carboxylic acid
  • 2,3,4,5-TETRAHYDRO-7-METHOXY-1H-BENZO[D]AZEPINE
  • 8-Methoxy-2,3,4,5-tetrahydro-1H-2-benzazepine

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and dopaminergic activity of 2-substituted octahydrobenzo[f]quinolines.

J. Med. Chem. 32 , 961, (1989)

A series of 2-substituted octahydrobenzo[f]quinolines has been synthesized and assayed for dopamine agonist activity. Only the compounds corresponding to the beta-rotameric conformation of dopamine sh...

8,9-methylenedioxybenzo[i]phenanthridines: topoisomerase I-targeting activity and cytotoxicity.

Bioorg. Med. Chem. 11(17) , 3795-3805, (2003)

Substituted benzo[i]phenanthridines that have incorporated within their structure an 8,9-methylenedioxy group can exhibit topoisomerase I-targeting activity. Structure-activity studies were performed ...


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Related Compounds

  • 2-(1-Amino-2,2-dimethylpropyl)-4-butylphenol
  • 2-(1-Aminoethyl)-6-chloro-4-phenylphenol
  • 2-(1-Amino-2-methylpropyl)-3,4,6-trichlorophenol
  • 4-[Amino(phenyl)methyl]-2,3-dimethylphenol
  • 2-[Amino(phenyl)methyl]-4-(2-methoxyethyl)phenol
  • Chloromethyl 2-{[(tert-butoxy)carbonyl]amino}-3-hydroxy-3-methylbutanoate
  • 2-(1-Amino-2,2-dimethylpropyl)-4-(2-methoxyethyl)phenol
  • 5-{[(Propoxymethyl)sulfanyl]methyl}furan-2-carboxylic acid
  • {1,4-Dioxa-9-thiaspiro[5.5]undecan-2-yl}methanamine
  • 5-formyl-1-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid
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