Cyproheptadine hydrochloride

Suppliers

Names

[ Name ]:
Cyproheptadine hydrochloride

[Synonym ]:
MFCD00012538
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-piperidine hydrochloride hydrate
Cyproheptadine hydrochloride sesquihydrate
Cyproheptadine hydrochloride
Piperidine (4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl
EINECS 213-535-1
Periactin
4-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride hydrate (2:2:3)
Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3)
Cyproheptadine (hydrochloride sesquihydrate)

Chemical & Physical Properties

[ Boiling Point ]:
440.1ºC at 760 mmHg

[ Melting Point ]:
165 °C (dec.)(lit.)

[ Molecular Formula ]:
C₂₁H₂₁N_.3/₂H₂O_.HCl

[ Molecular Weight ]:
350.88

[ Flash Point ]:
194.5ºC

[ PSA ]:
12.47000

[ LogP ]:
5.37350

[ Water Solubility ]:
ethanol: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
TM7050000

Articles

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug Metab. Dispos. 38 , 2302-8, (2010)

Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...