2,4,6-Trichlorobenzoyl chloride

Names

[ Name ]:
2,4,6-Trichlorobenzoyl chloride

[Synonym ]:
2,4,6-Trichlorobenzoylchloride
2,4,6-Trichlorobenzoyl chloride
MFCD00075323
Benzoyl chloride, 2,4,6-trichloro-

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
284.2±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₂Cl₄O

[ Molecular Weight ]:
243.902

[ Flash Point ]:
118.5±26.5 °C

[ Exact Mass ]:
241.885971

[ PSA ]:
17.07000

[ LogP ]:
3.36

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.590

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S28-S36/37/39-S45-S25

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2,4,6-Trichlorobenzoic acid
2-bromo-6-chloro-4-methylaniline
2-bromo-6-chloro-4-methylbenzonitrile
2-bromo-6-chloro-4-methylbenzamide
2-Chloro-4-methylaniline
2,4,6-Trichlorobenzonitrile

DownStream

2,4,6-Trichlorobenzoic acid
1-(2,4,6-Trichlorophenyl)ethanone

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Novel synthetic method for the preparation of amphiphilic hyaluronan by means of aliphatic aromatic anhydrides.

Carbohydr. Polym. 111 , 883-91, (2014)

The present work describes a novel and efficient method of synthesis of amphiphilic hyaluronan (HA) by esterification with alkyl fatty acids. These derivatives were synthesized under mild aqueous and ...

Asymmetric total synthesis of spongistatins 1 and 2.

J. Am. Chem. Soc. 124(20) , 5661-63, (2002)

The total synthesis of spongistatin 1 (1) and spongistatin 2 (2) has been achieved through an advanced-stage intermediate. The synthesis is highlighted by a highly convergent assembly of the four key ...

Synthesis of γ- and δ-lactone natural products by employing a trans-cis isomerization/lactonization strategy.

Chem. Pharm. Bull. 61(4) , 464-70, (2013)

Alkaline hydrolysis of 4-hydroxy- or/and 5-hydroxy-(2E)-alkenoate followed by acid treatment gave the corresponding (2E)-alkenoic acids which were subjected to lactone formation reaction without furth...

2,4,6-trichlorobenzoyl chloride
5-[(2,4,6-Trichlorobenzoyl)amino]-1,3-thiazole-4-carboxylic acid
cinnamoyl 2,4,6-trichlorobenzoyl mixed anhydride
Ethyl 5-[(2,4,6-trichlorobenzoyl)amino]-1,3-thiazole-4-carboxylate
2-[5-methoxy-2-methyl-1-(2,4,6-trichlorobenzoyl)indol-3-yl]acetic acid
2,4,6-TRIISOPROPYLBENZOYL CHLORIDE
N-(4-bromo-2-fluorophenyl)-1-(5-methoxybenzo[d]thiazol-2-yl)azetidine-3-carboxamide
(4-Phenethylpiperazin-1-yl)(6-(pyrrolidin-1-yl)pyridazin-3-yl)methanone
N-cyclopropyl-6-(pyrrolidin-1-yl)pyridazine-3-carboxamide
9-(Thiophen-2-ylmethyl)-9-azabicyclo[3.3.1]nonan-3-amine dihydrochloride
Ethyl 2-(6-(pyrrolidin-1-yl)pyridazine-3-carboxamido)thiazole-4-carboxylate
N-(isoxazol-3-yl)-6-(pyrrolidin-1-yl)pyridazine-3-carboxamide
N-(4-(furan-2-yl)thiazol-2-yl)-6-(pyrrolidin-1-yl)pyridazine-3-carboxamide
N-(4-(N-(4-methylpyrimidin-2-yl)sulfamoyl)phenyl)-6-(pyrrolidin-1-yl)pyridazine-3-carboxamide
N-(2,3-dichlorophenyl)-6-(pyrrolidin-1-yl)pyridazine-3-carboxamide
(3-(1H-tetrazol-1-yl)phenyl)(4-(2-(2-phenyl-1H-imidazol-1-yl)ethyl)piperazin-1-yl)methanone

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