ROSE BENGAL LACTONE

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Names

[ CAS No. ]:
4159-77-7

[ Name ]:
ROSE BENGAL LACTONE

[Synonym ]:
3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
rose bengal B
4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Solvent Red 141
2,4,5,7-Tetraiodo-3,6-dihydroxy-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
BENGAL RED B
2,4,5,7-tetraiodo-3',4',5',6'-tetrachlorofluorescein
4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
EINECS 223-993-4
4,5,6,7-tetrachloro-2',4',5',7'-tetraiodofluorescein
MFCD00013321

Chemical & Physical Properties

[ Density]:
2.96g/cm3

[ Boiling Point ]:
741.8ºC at 760 mmHg

[ Melting Point ]:
280ºC (dec.)(lit.)

[ Molecular Formula ]:
C20H4Cl4I4O5

[ Molecular Weight ]:
973.67300

[ Flash Point ]:
402.4ºC

[ Exact Mass ]:
971.49900

[ PSA ]:
75.99000

[ LogP ]:
8.69780

[ Index of Refraction ]:
1.955

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Rose Bengal sodium

DownStream

  • Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-, potassium salt(1:2)
  • Rose Bengal sodium
  • ROSE BENGAL BIS(TRIETHYLAMMONIUM) SALT
  • Rose Bengal diacetate

Articles

The promoting effects of food dyes, erythrosine (Red 3) and rose bengal B (Red 105), on thyroid tumors in partially thyroidectomized N-bis(2-hydroxypropyl)-nitrosamine-treated rats.

Jpn. J. Cancer Res. 79(3) , 314-9, (1988)

The effects of erythrosine (Red 3), rose bengal B (Red 105) and thyroidectomy on the development of thyroid tumor were examined in male Wistar rats treated with N-bis(2-hydroxypropyl)nitrosamine (DHPN...

[A laboratory method for sensitized isomerization of polyene macrolides].

Antibiot. Khimioter. 41(2) , 16-21, (1996)

The study was aimed at the development of a laboratory procedure for isomerization of polyene macrolides in the presence of sensitizers. The reaction was performed with exposure of levorin solutions t...

Induction of thyroid tumors in (C57BL/6N x C3H/N)F1 mice by oral administration of 9-3',4',5',6'-tetrachloro-o-carboxy phenyl-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone sodium (Food Red 105, rose bengal B).

J. Natl. Cancer Inst. 77(1) , 277-81, (1986)

The tumorigenicity of 9-3',4',5',6'-tetrachloro-o-carboxy phenyl-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone sodium (CAS: 632-68-8) [also called Food Red 105 (FR 105) or Rose Bengal B], which is widely ...


More Articles

Related Compounds

  • Rose Bengal diacetate
  • Rose Bengal sodium
  • ROSE BENGAL BIS(TRIETHYLAMMONIUM) SALT
  • Rose Bengal benzyl ester, monosodium salt
  • Rose Bengal Sodium
  • Rose Bengal benzyl ester
  • 1-Methoxy-3-(trifluoroprop-1-YN-1-YL)benzene
  • Tert-butyl 2-amino-2-cyclopentylacetate
  • Methyl 3-(adamantan-1-yl)-2-aminopropanoate
  • N-benzyl-N-(3-methyl-1,2-oxazol-4-yl)formamide
  • 6-methanesulfinyl-1H-indole
  • 4-chloro-5H-pyridazino[4,5-b]indole
  • 1-(2-chlorobenzyl)-3-(3,4,5-trimethoxyphenyl)quinazoline-2,4(1H,3H)-dione
  • 4-Aminocyclopent-1-ene-1-carboxylic acid hydrochloride
  • 7-(4H-1,2,4-triazol-4-yl)pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one
  • 2-(Methylthio)-3-(trifluoromethyl)pyridine
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