ROSE BENGAL LACTONE

Names

[ Name ]:
ROSE BENGAL LACTONE

[Synonym ]:
3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
rose bengal B
4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Solvent Red 141
2,4,5,7-Tetraiodo-3,6-dihydroxy-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
BENGAL RED B
2,4,5,7-tetraiodo-3',4',5',6'-tetrachlorofluorescein
4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
EINECS 223-993-4
4,5,6,7-tetrachloro-2',4',5',7'-tetraiodofluorescein
MFCD00013321

Chemical & Physical Properties

[ Density]:
2.96g/cm3

[ Boiling Point ]:
741.8ºC at 760 mmHg

[ Melting Point ]:
280ºC (dec.)(lit.)

[ Molecular Formula ]:
C₂₀H₄Cl₄I₄O₅

[ Molecular Weight ]:
973.67300

[ Flash Point ]:
402.4ºC

[ Exact Mass ]:
971.49900

[ PSA ]:
75.99000

[ LogP ]:
8.69780

[ Index of Refraction ]:
1.955

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

The promoting effects of food dyes, erythrosine (Red 3) and rose bengal B (Red 105), on thyroid tumors in partially thyroidectomized N-bis(2-hydroxypropyl)-nitrosamine-treated rats.

Jpn. J. Cancer Res. 79(3) , 314-9, (1988)

The effects of erythrosine (Red 3), rose bengal B (Red 105) and thyroidectomy on the development of thyroid tumor were examined in male Wistar rats treated with N-bis(2-hydroxypropyl)nitrosamine (DHPN...

[A laboratory method for sensitized isomerization of polyene macrolides].

Antibiot. Khimioter. 41(2) , 16-21, (1996)

The study was aimed at the development of a laboratory procedure for isomerization of polyene macrolides in the presence of sensitizers. The reaction was performed with exposure of levorin solutions t...

Induction of thyroid tumors in (C57BL/6N x C3H/N)F1 mice by oral administration of 9-3',4',5',6'-tetrachloro-o-carboxy phenyl-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone sodium (Food Red 105, rose bengal B).

J. Natl. Cancer Inst. 77(1) , 277-81, (1986)

The tumorigenicity of 9-3',4',5',6'-tetrachloro-o-carboxy phenyl-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone sodium (CAS: 632-68-8) [also called Food Red 105 (FR 105) or Rose Bengal B], which is widely ...