L-Glutamic acid der.

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Names

[ CAS No. ]:
41600-13-9

[ Name ]:
L-Glutamic acid der.

[Synonym ]:
4-Amino-4-deoxy-N10-methylpteroylglutamyl-g-glutamate
MTX diglutamate
4-NH2-10-CH3-folyldiglutamate
4-amino-10-methylpteroyldiglutamate
L-Glutamic acid,N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-g-glutamyl

Chemical & Physical Properties

[ Density]:
1.539g/cm3

[ Molecular Formula ]:
C25H29N9O8

[ Molecular Weight ]:
583.55300

[ Exact Mass ]:
583.21400

[ PSA ]:
276.94000

[ LogP ]:
1.56220

[ Index of Refraction ]:
1.704

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Methylamino-benzoic acid
  • H-Glu-Obzl
  • Benzoic acid,4-[methyl[(phenylmethoxy)carbonyl]amino]-
  • benzyl N-[(4-carbonochloridoylphenyl)methyl]carbamate
  • N-[N-[4-[[(benzyloxy)carbonyl]methylamino]benzoyl]-L-γ-glutamyl]-L-glutamic acid tribenzyl ester

DownStream

Related Compounds

  • L-GlutaMic acid-3-13C
  • L-Glutamic acid,N-[4-[[(2-amino-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-6-yl)methyl]amino]benzoyl]-
  • L-Glutamic acid,N-[4-[2-(2-amino-3,4-dihydro-4-oxo-6-quinazolinyl)ethyl]benzoyl]-
  • L-Glutamic acid,N,N-bis(phenylmethyl)-
  • L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]ethylamino]benzoyl]-, diethyl ester(9CI)
  • L-Glutamic acid,N-benzoyl-, 5-methyl ester
  • 3-hydroxy-2-(N-hydroxy-C-methylcarbonimidoyl)-4,4,6-trimethylcyclohex-2-en-1-one
  • Imidazo[1,2-a]pyridine-2-carboxylic acid, 3-hydroxy-
  • 3-(Chloromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
  • 1-[(2,2-Dimethylcyclopropyl)methyl]-4-methylpiperazine
  • 10-Methyl-1-oxaspiro[5.5]undecan-7-one
  • 8-Iodo-2-methyl-3H-quinazolin-4-one
  • Methyl 2-(4-amino-2-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)acetate
  • 1-(5-Amino-2-(chloromethyl)phenyl)-3-bromopropan-2-one
  • 5-(1h-Pyrazol-4-yl)pyrimidine
  • ethyl (2S)-2-(4-oxocyclohexyl)propanoate
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