Lenvatinib (E7080)

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Names

[ CAS No. ]:
417716-92-8

[ Name ]:
Lenvatinib (E7080)

[Synonym ]:
4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide
UNII-EE083865G2
E7080
MFCD16038644
Lenvatinib
4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
6-Quinolinecarboxamide, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-
Lenvatinib (E7080)

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
627.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H19ClN4O4

[ Molecular Weight ]:
426.853

[ Flash Point ]:
333.1±31.5 °C

[ Exact Mass ]:
426.109497

[ PSA ]:
115.57000

[ LogP ]:
3.39

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.697

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl)oxy-2-chlorophenyl)carbamate
  • Cyclopropanamine

DownStream

  • Lenvatinib Mesylate

Related Compounds

  • Lenvatinib Impurity 5
  • Lenvatinib Mesylate
  • Lenvatinib Impurity 6
  • Lenvatinib Impurity 7
  • 6-Carbamoyl-4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline 1-oXnde
  • Lenvatinib Impurity 2