PYR-41

Suppliers

Names

[ Name ]:
PYR-41

[Synonym ]:
Ethyl 4-{(4Z)-4-[(5-nitro-2-furyl)methylene]-3,5-dioxo-1-pyrazolidinyl}benzoate
4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester
Benzoic acid, 4-[(4Z)-4-[(5-nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]-, ethyl ester
PYR-41

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₁₇H₁₃N₃O₇

[ Molecular Weight ]:
371.301

[ Exact Mass ]:
371.075348

[ PSA ]:
134.67000

[ LogP ]:
2.87

[ Appearance of Characters ]:
red to brown

[ Index of Refraction ]:
1.652

[ Storage condition ]:
?20°C

[ Water Solubility ]:
Soluble in DMSO at 5mg/ml with warming

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317

[ Precautionary Statements ]:
P280

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-43

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells.

Oncotarget 6 , 17221-36, (2015)

The cold and menthol receptor TRPM8 is highly expressed in prostate and prostate cancer (PC). Recently, we identified that TRPM8 is as an ionotropic testosterone receptor. The TRPM8 mRNA is expressed ...

Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.

Proteomics 14(20) , 2297-306, (2014)

Exosomes are small vesicles secreted from cells that transport their embedded molecules through bidirectional exocytosis- and endocytosis-like pathways. Expression patterns of exosomal molecules such ...

Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway.

J. Neurosci. 36 , 1930-41, (2016)

Failure to clear amyloid-β (Aβ) from the brain is in part responsible for Aβ brain accumulation in Alzheimer's disease (AD). A critical protein for clearing Aβ across the blood-brain barrier is the ef...