3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine

Names

[ CAS No. ]:
41945-37-3

[ Name ]:
3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine

[Synonym ]:
3-Brom-5,7-dimethyl-pyrazolo<1,5-a>pyrimidin
Pyrazolo(1,5-a)pyrimidine,3-bromo-5,7-dimethyl
3-bromo5,7-dimethylpyrazolo[1,5-a]pyrimidine

Chemical & Physical Properties

[ Density]:
1.67g/cm3

[ Molecular Formula ]:
C8H8BrN3

[ Molecular Weight ]:
226.07300

[ Exact Mass ]:
224.99000

[ PSA ]:
30.19000

[ LogP ]:
2.10860

[ Index of Refraction ]:
1.687

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR0720000
CHEMICAL NAME :
Pyrazolo(1,5-a)pyrimidine, 3-bromo-5,7-dimethyl-
CAS REGISTRY NUMBER :
41945-37-3
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H8-Br-N3
MOLECULAR WEIGHT :
226.10
WISWESSER LINE NOTATION :
T56 ANN FNJ DE G1 I1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1346 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,386,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
458 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,386,1977

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid
  • (7-bromo-2,4-dimethyl-1,5,9-triazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)oxy-diethoxy-sulfanylidene-phosphorane
  • 3-bromo-5,6-dimethylpyrazolo[1,5-a]pyrimidine
  • 3-Chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid
  • 3-iodo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
  • 3-chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-{1-tert-butyl-1H-pyrazolo[3,4-c]pyridin-4-yl}pyrrolidin-3-ol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide