UNII:Q2E57V2WS3

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Names

[ Name ]:
UNII:Q2E57V2WS3

[Synonym ]:
(±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
UNII:Q2E57V2WS3
DOI hydrochloride,4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
1-(4-Iodo-2,5-dimethoxyphenyl)propan-2-amine hydrochloride (1:1)
1-(4-Iodo-2,5-dimethoxyphenyl)-2-propanamine hydrochloride (1:1)
Benzeneethanamine, 4-iodo-2,5-dimethoxy-α-methyl-, hydrochloride (1:1)
(±)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
361.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₇ClINO₂

[ Molecular Weight ]:
357.616

[ Flash Point ]:
172.5ºC

[ Exact Mass ]:
356.999237

[ PSA ]:
44.48000

[ LogP ]:
3.70040

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(+/-)-N-acetyl-1-(2,5-dimethoxyphenyl)-2-aminopropane
(+/-)-N-acetyl-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane

DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex.

J. Pharmacol. Exp. Ther. 278 , 1373-1382, (1996)

Correlations between 5-hydroxytryptamine (5-HT) receptor binding affinities and human hallucinogenic potency have suggested that 5-HT2 receptors mediate the hallucinogenic effects of lysergic acid die...

Effect of the selective 5-HT receptor agonists 8-OHDPAT and DOI on behavior and brain biogenic amines of rats.

Gen. Pharmacol. 28 , 583-587, (1997)

1. The behavioral responses, as well as the biogenic amines and metabolite contents in discrete brain areas were determined in male rats subcutaneously treated with a 5-HT1A (8-OHDPAT) or 5-HT2A (DOI)...

DOI, a 5-HT2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat striatum.

Brain Res. 698 , 204-208, (1995)

The effects of (+-)-DOI (1-(2,5-dimethoxy-4-iodophenyl)-aminopropane) hydrochloride, a mixed 5-HT2A/2C receptor agonist, on the release of dopamine (DA) following D-amphetamine sulfate (AMP) or a DA D...

4-{3-Cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-2-(4,4-difluoropiperidine-1-carbonyl)morpholine
3-(2-Methoxyethoxy)oxan-4-one
N-(1-{pyrido[3,4-d]pyrimidin-4-yl}piperidin-4-yl)cyclopropanesulfonamide
1-[3-Bromo-5-(trifluoromethyl)pyridin-2-yl]-4-(cyclopropanesulfonyl)-1,4-diazepane
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-cyclopentyl-1,3-thiazole-5-carboxylate
4-(6-cyclopropyl-1,8-naphthyridin-2-yl)-N-(propan-2-yl)piperidine-1-carboxamide
1-(2,3-dihydro-1H-indol-1-yl)-2-[4-(1,3-thiazol-2-yloxy)piperidin-1-yl]ethan-1-one
2-[(2S)-1-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]butanoyl}piperidin-2-yl]acetic acid
4-(2-methoxy-5-nitrophenyl)-1H-imidazole
5-(3-fluorophenyl)-1H-indene

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