5-methyl-1-[4-methylsulfonyloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

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Names

[ CAS No. ]:
42214-24-4

[ Name ]:
5-methyl-1-[4-methylsulfonyloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

[Synonym ]:
3'-O-(methylsulfonyl)-5'-O-trityl-2'-deoxythymidine
O3'-methanesulfonyl-O5'-trityl-thymidine
5'-O-TRITYL-3'-O-MESYLTHYMIDINE
3'-O-mesyl-5'-O-tritylthymidine

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Molecular Formula ]:
C30H30N2O7S

[ Molecular Weight ]:
562.63300

[ Exact Mass ]:
562.17700

[ PSA ]:
125.33000

[ LogP ]:
4.97910

[ Index of Refraction ]:
1.654

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanesulfonyl chloride
  • 5'-O-Tritylthymidine
  • Triphenylmethyl Chloride
  • Thymidine

DownStream

  • [(2R,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] thiocyanate
  • 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE
  • 3'-Amino-3'-deoxythymidine
  • Stavudine
  • Alovudine
  • 5'-O-Tritylthymidine
  • 5-O-Triphenylmethyl-2-deoxy-2,3-didehyrothymidine
  • 5'-o-trityl-2',3'-dehydrothymidine
  • 5'-O-TRITYL-2'-DEOXY-BETA-D-LYXOFURANOSYLTHYMINE