1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

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Names

[ CAS No. ]:
4235-95-4

[ Name ]:
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

[Synonym ]:
Ethanaminium, 2-[[[(2R)-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
EINECS 224-193-8
MFCD00135191
(2R)-2,3-Bis[(9Z)-9-octadecenoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine DOPC
(R)-2,3-Bis(oleoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate
(2R)-2,3-Bis[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate

Chemical & Physical Properties

[ Molecular Formula ]:
C44H84NO8P

[ Molecular Weight ]:
786.113

[ Exact Mass ]:
785.593445

[ PSA ]:
121.00000

[ LogP ]:
11.97

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
36/37

[ RIDADR ]:
UN 1888 6

[ HS Code ]:
2923900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • oleic acid
  • Choline glycerophosphate
  • 1,2-Dioleoyl-sn-glycerol
  • Trimethylamine
  • choline
  • 1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHATE SODIUM SALT
  • OLEIC ACID CHLORIDE
  • [(E)-octadec-9-enoyl] (E)-octadec-9-enoate

DownStream

  • DOPE
  • choline
  • (2S)-2-amino-4-((((R)-2,3-bis((E)-octadec-9-enoyloxy)propoxy)(hydroxy)phosphoryl)oxy)butanoic acid
  • oleic acid

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.

Biochim. Biophys. Acta 1838(10) , 2615-24, (2014)

We have studied the dynamics of Lissamine Rhodamine B dye sensitization-induced oxidation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) giant unilamellar vesicles (GUVs), where the progression of...

Unsaturated lipids protect the integral membrane peptide gramicidin A from singlet oxygen

FEBS Lett. 588(9) , 1590-5, (2014)

• Unsaturated lipids protect gramicidin channels from photosensitized inactivation. • Photosensitizer binding to membrane is independent of lipid unsaturation. • Double bonds in lipids reduce gramicid...

Antibiotic delivery by liposomes from prokaryotic microorganisms: Similia cum similis works better.

Eur. J. Pharm. Biopharm. 94 , 411-8, (2015)

To date the effectiveness of antibiotics is undermined by microbial resistance, threatening public health worldwide. Enhancing the efficacy of the current antibiotic arsenal is an alternative strategy...


More Articles

Related Compounds

  • 1,2-Dioleoyl-sn-glycero-3-phosphocholine
  • 1,2-Dioleoyl-sn-glycero-3-phosphoric acid disodium
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO[N-(4-CARBOXYBUTANOYL)ETHANOLAMINE]
  • 1,2-dioleoyl-sn-glycero-3-phospho-(1'-Myo-inositol-3',4'-bisphosphate) (amMonium salt)
  • 1,2-dioleoyl-sn-glycero-3-phospho-(1'-Myo-inositol-3',5'-bisphosphate) (amMonium salt)
  • 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, 7-nitrobenzofurazan-labeled