2-(2-Oxotetrahydrofuran-3-yl)-1H-isoindole-1,3(2H)-dione

Names

[ CAS No. ]:
42473-02-9

[ Name ]:
2-(2-Oxotetrahydrofuran-3-yl)-1H-isoindole-1,3(2H)-dione

[Synonym ]:
2-(2-oxooxolan-3-yl)isoindole-1,3-dione

Chemical & Physical Properties

[ Density]:
1.516g/cm3

[ Boiling Point ]:
448.7ºC at 760 mmHg

[ Molecular Formula ]:
C12H9NO4

[ Molecular Weight ]:
231.20400

[ Flash Point ]:
225.2ºC

[ Exact Mass ]:
231.05300

[ PSA ]:
63.68000

[ LogP ]:
0.53600

[ Index of Refraction ]:
1.653

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NR3402600
CHEMICAL NAME :
1H-Isoindole-1,3(2H)-dione, 2-(tetrahydro-2-oxo-3-furanyl)-
CAS REGISTRY NUMBER :
42473-02-9
BEILSTEIN REFERENCE NO. :
0022797
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H9-N-O4
MOLECULAR WEIGHT :
231.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,188,1981

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Bromdihydrofuran-2(3H)-on
  • Potassium phthalimide

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-(tert-butyl)-1-(3-chlorobenzyl)-7,9-dimethyl-7,9-dihydro-[1,2,4]triazino[3,4-f]purine-6,8(1H,4H)-dione
  • 3-(4-chlorobenzyl)-1,6,7-trimethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
  • 1-(2-fluorobenzyl)-3,4,7,9-tetramethyl-7,9-dihydro-[1,2,4]triazino[3,4-f]purine-6,8(1H,4H)-dione
  • CID 16610430
  • CID 16610431
  • 1,7-dimethyl-3-(naphthalen-1-ylmethyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
  • 6-(2,4-Dimethylphenyl)-2,4-dimethyl-7,8-dihydropurino[7,8-a]imidazole-1,3-dione
  • 3-(4-fluorophenyl)-1-isobutyl-7,9-dimethyl-7,9-dihydro-[1,2,4]triazino[3,4-f]purine-6,8(1H,4H)-dione
  • 8-(2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-1,3,6,7-tetramethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
  • 8-(3-(dimethylamino)propyl)-3-(4-fluorobenzyl)-1,6,7-trimethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione