Activated protein C

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Names

[ CAS No. ]:
42617-41-4

[ Name ]:
Activated protein C

[Synonym ]:
MFCD00165567

Chemical & Physical Properties

[ Appearance of Characters ]:
lyophilized powder

[ Storage condition ]:
−20°C

Safety Information

[ Hazard Codes ]:
B

[ Risk Phrases ]:
36/37

[ Safety Phrases ]:
36/37-36-26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Protein C activation peptide inhibits the expression of ICAM-1, VCAM-1, and interleukin-8 induced by TNF-α in human dermal microvascular endothelial cells.

Folia Histochem. Cytobiol. 50 , 407-13, (2012)

Activated protein C (APC) is generated from the cleavage of protein C by thrombin coupled to thrombomodulin and, subsequently, is released as protein C activation peptide (papC). The aim of this study...

The regulation of natural anticoagulant pathways.

Science 235(4794) , 1348-52, (1987)

Vascular endothelium plays an active role in preventing blood clot formation in vivo. One mechanism by which prevention is achieved involves a cell surface thrombin-binding protein, thrombomodulin, wh...

The roles of protein C and thrombomodulin in the regulation of blood coagulation.

J. Biol. Chem. 264(9) , 4743-6, (1989)

N-[(1S)-1-Methyl-2-oxo-2-[4-(phenylmethyl)-1-piperazinyl]ethyl]-2-thiophenepropanamide
5-(2-Furanyl)-N-[(1S)-3-methyl-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-3-isoxazolecarboxamide
2-(2,5-Dichlorophenoxy)-1-[(2S)-2-[(4-methyl-1-piperidinyl)carbonyl]-1-pyrrolidinyl]ethanone
N-[3-(4-Acetyl-1-piperazinyl)-3-oxopropyl]-1,2-dihydro-3-methyl-2-oxo-6-quinolineacetamide
N-[(1S)-2-Hydroxy-1-methylethyl]-4-methoxybenzenepentanamide
4-(Cyclopentyloxy)-N-[(1S)-2-hydroxy-1-methylethyl]-2-methylbenzenesulfonamide
I+/--(4-Fluorophenyl)-N-(2-thiazolo[3,2-b][1,2,4]triazol-6-ylethyl)-2-pyridinepropanamide
[1-(3-Bromophenyl)-2,2-dimethylcyclopropyl]methanol
[2,2-Dimethyl-1-(5-methylfuran-2-yl)cyclopropyl]methanol
1-(3-(Difluoromethoxy)-2-nitrophenyl)propan-1-one

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