NS3694

Names

[ CAS No. ]:
426834-38-0

[ Name ]:
NS3694

[Synonym ]:
Apoptosis Inhibitor II,NS3694
NS3694

Chemical & Physical Properties

[ Density]:
1.574g/cm3

[ Boiling Point ]:
378.448ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₀ClF₃N₂O₃

[ Molecular Weight ]:
358.70000

[ Flash Point ]:
182.679ºC

[ Exact Mass ]:
358.03300

[ PSA ]:
78.43000

[ LogP ]:
4.84700

[ Index of Refraction ]:
1.638

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production.

Biochem. Biophys. Res. Commun. 463 , 545-50, (2015)

In the current study, we investigated the potential activity of AR-42, a novel histone deacetylase (HDAC) inhibitor, against colon cancer cells. Our in vitro results showed that AR-42 induced ceramide...

An epistatic effect of apaf-1 and caspase-9 on chlamydial infection.

Apoptosis 20 , 1271-80, (2015)

Chlamydia is an obligate intracellular bacterial pathogen that replicates solely within a membrane-bound vacuole termed an inclusion. Chlamydia seems to perturb multiple cellular processes of the host...

Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide.

PLoS Pathog. 11 , e1004853, (2015)

Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of tim...