Flumequine

Suppliers

Names

[ Name ]:
Flumequine

[Synonym ]:
Apurone
UNII:UVG8VSP2SJ
Quinolone
9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid
FLUMEQUIN
Flumeguine
EINECS 255-962-6
1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo-
9-Fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
MFCD00079298
Imequyl
9-Fluoro-1,5,6,7-tetrahydro-5-methyl-1-oxopyrido[3,2,1-ij]quinoline-2-carboxylic Acid
Flumural
Flumequine
Aoyribe
Fantacin
R 802

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
439.7±45.0 °C at 760 mmHg

[ Melting Point ]:
253-255°C

[ Molecular Formula ]:
C₁₄H₁₂FNO₃

[ Molecular Weight ]:
261.248

[ Flash Point ]:
219.7±28.7 °C

[ Exact Mass ]:
261.080109

[ PSA ]:
59.30000

[ LogP ]:
2.41

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.646

[ Storage condition ]:
0-6°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ Hazard Class ]:
6.1

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline
Diethyl ethoxymethylenemalonate
5- [1-(6-fluoro-2-methyl-1,2,3,4-tetrahydroquinolyl)] -methylene-2,2-dimethyl-1,3-dioxan-4,6-dione
9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid ethyl ester
5-(Methoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

J. Med. Chem. 48 , 3269-79, (2005)

Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm...

QSAR-based solubility model for drug-like compounds.

Bioorg. Med. Chem. 18 , 7078-84, (2010)

Solubility plays a very important role in the selection of compounds for drug screening. In this context, a QSAR model was developed for predicting water solubility of drug-like compounds. First, a se...

gyrA and parC Mutations and associated quinolone resistance in Vibrio anguillarum serotype O2b strains isolated from farmed Atlantic cod (Gadus morhua) in Norway.

Antimicrob. Agents Chemother. 51 , 2597-9, (2007)

MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of < or =0.001, 0.06, and 16 microg ml(-1). Single gyrA Ser-Ile substitutions were id...

(S)-FluMequine
(R)-flumequine
Flumequine-13C3
Flumequine sodium
2-(benzylthio)-N-(2-(3-(trifluoromethyl)-1H-pyrazol-1-yl)ethyl)acetamide
1-(3-Bromo-5-fluorophenyl)-2-methylpropan-2-ol
Ethyl 6,7-dihydro-4-methyl-1H-indole-2-carboxylate
Methyl 2-amino-3-(5-methylpyridin-3-yl)propanoate
4-(1-Aminopropan-2-yl)piperidin-4-ol
2-Fluoro-N inverted exclamation mark-hydroxy-5-methoxybenzimidamide
2-Hydroxy-3-iodo-N-methylbenzamide
1-Tert-butoxy-4-cyclopropoxy-2-(trifluoromethyl)benzene
Methyl 2-hydroxy-4-methylcyclohexane-1-carboxylate
N-(3,4-Difluorophenyl)-2-{[2-(3,4-dimethylphenyl)pyrazolo[1,5-A]pyrazin-4-YL]sulfanyl}acetamide

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