(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid

Suppliers

Names

[ CAS No. ]:
4298-08-2

[ Name ]:
(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid

[Synonym ]:
D-Proline, 3-hydroxy-, (3S)-
3-(R)-hydroxy-2-(S)-proline
trans-3-hydroxy-(S)-proline
trans-3-Hydroxy-prolin
(2S,3S)-3-hydroxyproline
(3S)-3-Hydroxy-D-proline
L-3-HYDROXYPROLINE
3(S)-trans-hydroxy-L-proline
H-3-HYP-OH
MFCD00216471
TRANS-3-HYDROXY-L-PR
L-3-TRANS-HYDROXYPROLINE
trans-3-Hydroxy-L-proline
L-trans-3-hydroxyproline
trans-3-Hydroxyproline
(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid
H-HYP(3)-OH
H-PRO(3-HYDROXY)-OH
(3S)-3-Hydroxy-L-proline
3-Hydroxy-L-proline

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
355.2±42.0 °C at 760 mmHg

[ Melting Point ]:
235ºC

[ Molecular Formula ]:
C5H9NO3

[ Molecular Weight ]:
131.130

[ Flash Point ]:
168.6±27.9 °C

[ Exact Mass ]:
131.058243

[ PSA ]:
69.56000

[ LogP ]:
-1.66

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.540

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • potassium (2S,3S)-2-amino-3-hydroxy-5,5-dimethoxypentanoate
  • Proline
  • (2S,3S)-1-(tert-butoxycarbonyl)-3-(tert-butyldimethylsiloxy)pyrrolidine-2-carboxylic acid
  • [S]-3-Phenyl-1,7a-dihydro-pyrrolo[1,2-c]oxazol-5-one
  • (3R,7AS)-3-PHENYLTETRAHYDROPYRROLO[1,2-C]OXAZOL-5(3H)-ONE
  • (2R,3S)-1-benzyl-3-tert-butyldimethylsilyloxy-2-hydroxymethylpyrrolidine

DownStream

  • (2S,3R)-1-(TERT-BUTOXYCARBONYL)-3-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
  • (2S,3S)-1-(TERT-BUTOXYCARBONYL)-3-HYDROXYPYRROLIDINE-2-CARBOXYLICACIDMETHYLESTER
  • (2S,3S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-hydroxypyrrolidine-2-carboxylic acid
  • (3S)-3-Fluoro-L-proline
  • (2S,3S)-1-(TERT-BUTOXYCARBONYL)-3-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
  • (2S,3R)-N-TERT-BUTOXYCARBONYL-3-BENZOYLOXY-2-PYRROLIDINECARBOXYLICACIDMETHYLESTER
  • (2S,3S)-3-Hydroxypyrrolidine-2-carboxamide

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid
  • Boc-(2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid
  • Fmoc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid
  • BOC-(2S,3S)-3-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER
  • (2s,3s)-3-hydroxypyrrolidine-2-carboxylic acid; trifluoroacetic acid
  • (2S,3S)-3-hydroxy-1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester