Ketotifen Impurity G

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Names

[ CAS No. ]:
43076-16-0

[ Name ]:
Ketotifen Impurity G

[Synonym ]:
4-(1-Methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-9,10-dione
4H-Benzo[4,5]cyclohepta[1,2-b]thiophene-9,10-dione, 4-(1-methyl-4-piperidinylidene)-
10-(1-methylpiperidin-4-ylidene)benzo[1,2]cyclohepta[3,4-b]thiophene-4,5-dione
4-(1-Methyl-4-piperidinylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-9,10-dione
Ketotifen impurity G

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
505.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H17NO2S

[ Molecular Weight ]:
323.409

[ Flash Point ]:
259.7±30.1 °C

[ Exact Mass ]:
323.097992

[ PSA ]:
65.62000

[ LogP ]:
4.22

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.656

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • magnesium,1-methylpiperidin-4-ide,chloride
  • 10-bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-one
  • 4-(10-bromo-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methyl-piperidine
  • Ketotifen
  • 4H-Benzo[4,5]cyclohepta[1,2-b]thiophene-4-ol,10-methoxy-4-(1-methyl-4-piperidinyl)-
  • 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one

DownStream

Related Compounds

  • Chlorthalidone Impurity G
  • Lapatinib impurity G
  • satra impurity G, 1-(1-methyl-4-nitro-1H-imidazol-2-yl)-3-(methylsulfonyl)imidazolidin-2-one
  • Ritonavir-Impurity G
  • Ebastine IMpurity G
  • 4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide