Ketotifen Impurity G

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Names

[ CAS No. ]:
43076-16-0

[ Name ]:
Ketotifen Impurity G

[Synonym ]:
4-(1-Methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-9,10-dione
4H-Benzo[4,5]cyclohepta[1,2-b]thiophene-9,10-dione, 4-(1-methyl-4-piperidinylidene)-
10-(1-methylpiperidin-4-ylidene)benzo[1,2]cyclohepta[3,4-b]thiophene-4,5-dione
4-(1-Methyl-4-piperidinylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-9,10-dione
Ketotifen impurity G

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
505.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H17NO2S

[ Molecular Weight ]:
323.409

[ Flash Point ]:
259.7±30.1 °C

[ Exact Mass ]:
323.097992

[ PSA ]:
65.62000

[ LogP ]:
4.22

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.656

[ Storage condition ]:
2-8°C

Synthetic Route

Precursor & DownStream

Precursor

  • magnesium,1-methylpiperidin-4-ide,chloride
  • 10-bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-one
  • 4-(10-bromo-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methyl-piperidine
  • Ketotifen
  • 4H-Benzo[4,5]cyclohepta[1,2-b]thiophene-4-ol,10-methoxy-4-(1-methyl-4-piperidinyl)-
  • 10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one

DownStream


Related Compounds

  • Chlorthalidone Impurity G
  • Lapatinib impurity G
  • satra impurity G, 1-(1-methyl-4-nitro-1H-imidazol-2-yl)-3-(methylsulfonyl)imidazolidin-2-one
  • Ritonavir-Impurity G
  • Ebastine IMpurity G
  • 4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-{Pyrazolo[1,5-a]pyrimidin-6-yl}cyclopropan-1-ol
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-Amino-4-chloro-2,3-dihydro-1H-inden-1-one
  • 1-(2,6-Dichloro-5-fluoropyridin-3-yl)ethan-1-amine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1,3-Propanediol, 2-(3-fluorophenyl)-2-[(4-hydroxyphenyl)methyl]-
  • 1,2-Benzenediamine, 3,4-dimethyl-5-nitro-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol