4-ethyl-4,6,7,8-tetrahydro-1H-pyrano[3,4-f]indolizine-3,10-dione

Names

[ CAS No. ]:
43083-10-9

[ Name ]:
4-ethyl-4,6,7,8-tetrahydro-1H-pyrano[3,4-f]indolizine-3,10-dione

[Synonym ]:
4-ethyl-1,6,7,8-tetrahydro-4H-pyrano[3,4-f]indolizine-3,10-dione
de-AB-deoxycamptothecin

Chemical & Physical Properties

[ Density]:
1.29g/cm3

[ Boiling Point ]:
549.3ºC at 760 mmHg

[ Molecular Formula ]:
C13H15NO3

[ Molecular Weight ]:
233.26300

[ Flash Point ]:
286ºC

[ Exact Mass ]:
233.10500

[ PSA ]:
48.30000

[ LogP ]:
1.34490

[ Index of Refraction ]:
1.591

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-(6-acetoxymethyl-1,8-dibromo-5-oxo-1,2,3,5-tetrahydro-indolizin-7-yl)-butyric acid methyl ester
  • dimethyl 3-chloro-2-pentenedioate
  • 4-(1-carbomethoxypropyl)-5-carbomethoxy-1,6-cyclopentano-2-pyridone

DownStream

  • (±)- 1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy
  • 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-
  • 4-ethyl-4-hydroxy-1,6,7,8-tetrahydropyrano[3,4-f]indolizine-3,10-dione

Related Compounds

  • 3-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridine-2-carbonyl]-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridine-2-carbonyl]-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentanecarbonyl]-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentanecarbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentanecarbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolane-3-carbonyl]-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxane-4-carbonyl]-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-{2-ethyl-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]butanoyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-dimethylpentanoyl]-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(methoxymethyl)butanamido]cyclobutane-1-carboxylic acid
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