Formohydroximic acid

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Names

[ CAS No. ]:
4312-87-2

[ Name ]:
Formohydroximic acid

[Synonym ]:
Hydroxyformaldehydeoxime
Hydroxyiminomethanol
Hydroxyaminomethanone
hydroxyaminoketone
formohydroxamic acid
N-formyl-hydroxylamine
Formohydroximic acid
Formohydroxamsaeure
Hydroxymethanoneoxime
formhydroxamic acid

Chemical & Physical Properties

[ Density]:
1.408g/cm3

[ Boiling Point ]:
251ºC at 760mmHg

[ Molecular Formula ]:
CH3NO2

[ Molecular Weight ]:
61.04000

[ Flash Point ]:
105.6ºC

[ Exact Mass ]:
61.01640

[ PSA ]:
49.33000

[ LogP ]:
0.14840

[ Index of Refraction ]:
1.407

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ4740000
CHEMICAL NAME :
Formhydroxamic acid
CAS REGISTRY NUMBER :
4312-87-2
BEILSTEIN REFERENCE NO. :
1698504
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C-H3-N-O2
MOLECULAR WEIGHT :
61.05
WISWESSER LINE NOTATION :
VHMQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
570 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APEPA2 Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle Pathologie. (Berlin, Ger.) V.254-263, 1966-69. For publisher information, see NSAPCC. Volume(issue)/page/year: 257,296,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
570 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 29,225,1973 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
500 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 26(3),9A,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
500 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
APEPA2 Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle Pathologie. (Berlin, Ger.) V.254-263, 1966-69. For publisher information, see NSAPCC. Volume(issue)/page/year: 257,296,1967
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
680 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 33,69C,1986

Safety Information

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Precursor

  • Ethyl chloroformate
  • Ethyl formate
  • nitromethane
  • Formaldehyde
  • Formic Acid
  • Methanol
  • Chloral hydrate
  • methylamine
  • Benzenesulfohydroxamic Acid

DownStream

  • N-Methylformanilide
  • Hydroxylamine
  • 2-Vinyltoluene
  • Formic Acid
  • nitrogen dioxide

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%