Betamicine [INN-French]

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Names

[ CAS No. ]:
43169-50-2

[ Name ]:
Betamicine [INN-French]

[Synonym ]:
Betamicin sulfate [USAN]
Betamicin sulfate
D-Streptamine,sulfate
GENTAMICIN B SULFATE

Chemical & Physical Properties

[ Boiling Point ]:
751.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₄₀N₄O₁₄S

[ Molecular Weight ]:
580.60400

[ Flash Point ]:
408.1ºC

[ Exact Mass ]:
580.22600

[ PSA ]:
331.37000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WK1974100

CHEMICAL NAME :: D-Streptamine, O-6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(3-d eoxy-4-C-methyl-3- (methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy- , sulfate

CAS REGISTRY NUMBER :: 43169-50-2

LAST UPDATED :: 199306

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H38-N4-O10.xH2-O4-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >301 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 2,464,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2106 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 2,464,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1805 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 2,464,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 274 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 2,464,1972

Related Compounds

Betamicine [INN-French]
Betamicine [INN-French]
(2S,5R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(4-oxo-1H-1,5-naphthyridine-3-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
biperiden
temocillin
Amogastrin
(1S)-3-amino-1-(furan-3-yl)propan-1-ol
(1R)-3-amino-1-(furan-3-yl)propan-1-ol
(1R)-3-amino-1-[3-(trifluoromethyl)phenyl]propan-1-ol
(1R)-3-amino-1-(1-benzothiophen-3-yl)propan-1-ol
5-Bromo-2-cyclobutoxybenzonitrile
(R)-Tert-Butyl 2-((methoxycarbonyl)methyl)morpholine-4-carboxylate
(S)-Tert-butyl 2-((methoxycarbonyl)methyl)morpholine-4-carboxylate
2-Ethoxy-5-(methoxymethyl)benzonitrile
Boron, [2-(amino-I masculineN)ethanolato-I masculineO][1,1-dimethylethyl (3S)-3-(hydroxy-I masculineO)pentanoato(2-)-I masculineC5]-, (T-4)-
(2-Cyclopropyl-5-(methoxymethyl)phenyl)methanamine

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