zopiclone n-oxide

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Names

[ CAS No. ]:
43200-96-0

[ Name ]:
zopiclone n-oxide

[Synonym ]:
OXZOP
Eszopiclone Impurity A
zopiclone-N-oxide
N-Oxidezopiclone

Chemical & Physical Properties

[ Melting Point ]:
>140ºC (dec.)

[ Molecular Formula ]:
C₁₇H₁₇ClN₆O₄

[ Molecular Weight ]:
404.80800

[ Flash Point ]:
9℃

[ Exact Mass ]:
404.10000

[ PSA ]:
117.95000

[ LogP ]:
1.54230

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P280-P302 + P352 + P312-P304 + P340 + P312-P370 + P378-P403 + P235

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-23/24/25-39/23/24/25

[ Safety Phrases ]:
7-16-36/37-45

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol

Articles

Determination of the enantiomers of zopiclone and its two chiral metabolites in urine using an automated coupled achiral-chiral chromatographic system.

J. Chromatogr. A. 617(2) , 271-8, (1993)

The enantiomers of zopiclone and its two chiral N-desmethyl and N-oxide metabolites were determined in urine using a coupled achiral-chiral liquid chromatographic method. After liquid-liquid extractio...

Capillary electrophoretic enantioselective determination of zopiclone and its impurities.

Electrophoresis 33(11) , 1606-12, (2012)

A capillary electrophoretic enantioselective method with UV detection was developed and validated for the simultaneous quantification of zopiclone enantiomers and its impurities, zopiclone-N-oxide ena...

Simultaneous determination of zopiclone and its two major metabolites (N-oxide and N-desmethyl) in human biological fluids by reversed-phase high-performance liquid chromatography.

J. Chromatogr. A. 417(1) , 151-8, (1987)

A high-performance liquid chromatographic method has been developed for the simultaneous determination of zopiclone and its main metabolites (N-oxide and N-desmethyl derivatives) in biological fluids....

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