Methotrexate-d3

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Names

[ CAS No. ]:
432545-63-6

[ Name ]:
Methotrexate-d3

Chemical & Physical Properties

[ Melting Point ]:
210°C dec.

[ Molecular Formula ]:
C20H19D3N8O5

[ Molecular Weight ]:
457.45800

[ Flash Point ]:
9℃

[ Exact Mass ]:
457.19000

[ PSA ]:
210.54000

[ LogP ]:
1.82170

[ Storage condition ]:
-20°C Freezer

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310 + P330-P308 + P311-P403 + P233

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-23/24/25-39/23/24/25

[ Safety Phrases ]:
7-16-36/37-45

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

Synthetic Route

Precursor & DownStream

Precursor

  • (2H2)Formaldehyde
  • Aminopterin

DownStream

  • dimethyl 2-[[4-[(2,4-diaminopteridin-6-yl)methyl-(trideuteriomethyl)amino]benzoyl]amino]pentanedioate

Articles

A surface wipe sampling and LC-MS/MS method for the simultaneous detection of six antineoplastic drugs commonly handled by healthcare workers.

Anal. Bioanal. Chem 407 , 7083-92, (2015)

An effective wipe sampling and LC-MS/MS method was developed to simultaneously analyze six commonly administered antineoplastic drugs in stainless steel surface. The analyzed drugs were methotrexate, ...


More Articles


Related Compounds

  • Dimethyl Methotrexate-d3
  • 7-Hydroxymethotrexate-d3
  • Methotrexate metabolite-d3
  • Methotrexate alpha-Methyl Ester
  • methotrexate dimethyl ester
  • Methotrexate disodium