3,5-DI-O-(P-TOLUYL)-2-DEOXY-D-RIBOFURANOSYL CHLORIDE

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Names

[ CAS No. ]:
4330-21-6

[ Name ]:
3,5-DI-O-(P-TOLUYL)-2-DEOXY-D-RIBOFURANOSYL CHLORIDE

[Synonym ]:
3,5-DI-O-(P-TOLUYL)-2-DEOXY-D-*RIBOFURAN OSYL CHLORI
Hoffer's chlorosugar
2-Deoxy-3,5-bis-O-(4-methylphenyl)-D-erythro-pentofuranosyl chloride
1-Chloro-2-deoxy-3,5-di-O-toluoyl-a-D-ribofuranose
D-erythro-Pentofuranosyl chloride, 2-deoxy-3,5-bis-O-(4-methylphenyl)-
1-CHLORO-3,5-BIS[O-(4-TOLUOYL)]-2-DEOXYRIBOSE
EINECS 224-367-3
1-Chloro-3,5-di-O-toluoyl-2-deoxy-a-D-ribofuranose
3,5-di-O-(P-toluyl)-2-deoxy-D-*ribofuranosyl chlo
(2R,5R)-5-chloro-2(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate
chlorosugar
3,5-Di-O-p-toluyl-2-deoxy-a-D-ribofuranosyl chloride
MFCD00079148
3,5-bis(toluoyl)-2-deoxyribosyl chloride

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
467.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H21ClO3

[ Molecular Weight ]:
332.821

[ Flash Point ]:
158.9±28.8 °C

[ Exact Mass ]:
332.117920

[ PSA ]:
27.69000

[ LogP ]:
4.39

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.578

[ Storage condition ]:
−20°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29321900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 2-deoxy-3,5-di-o-p-toluoyl-d-*rib ofuranoside
  • methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside
  • 2-deoxy-D-ribofuranose
  • p-toluoyl chloride
  • methyl 2-deoxy-3,5-di-O-p-toluoyl-β-D-erythropentofuranoside
  • 4-Methylbenzoic anhydride

DownStream

  • Cladribine
  • 7-Deaza-2'-dA
  • 1-(2-deoxyribofuranosyl)-4-(3-benzamido)phenylimidazole
  • Aids186752
  • 3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside
  • 3,5-O-Ditoluoyl 6-Chloropurine-7-β-D-deoxyriboside
  • (4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
  • 2'-Deoxyadenosine
  • 2'-deoxy-3',5'-di-o-(4-methylbenzoyl)-5-ethyluridine

Related Compounds

  • Methyl 2-acetyl-5,5-dimethyl-4-oxoheptanoate
  • Methyl 4-oxo-2-propanoylheptanoate
  • Ethyl 2-butanoyl-6,6-dimethyl-4-oxoheptanoate
  • Ethyl 2-(2-cyclopentyl-2-oxoethyl)-4-methyl-3-oxopentanoate
  • 5-(4-methanesulfonyl-1H-pyrazol-1-yl)-1-(methylamino)pentan-2-ol
  • 1-(4-methanesulfonyl-1H-pyrazol-1-yl)-3-[(propan-2-yl)amino]propan-2-ol
  • N-ethyl-3-(4-methanesulfonyl-1H-pyrazol-1-yl)cyclopentan-1-amine
  • 3-amino-2-(4-methanesulfonyl-1H-pyrazol-1-yl)-4,4-dimethylpentan-1-ol
  • [3-(4-methanesulfonyl-1H-pyrazol-1-yl)butan-2-yl](methyl)amine
  • [3-(4-methanesulfonyl-1H-pyrazol-1-yl)propyl](2-methoxyethyl)amine
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