Fangchinoline

Suppliers

Names

[ CAS No. ]:
436-77-1

[ Name ]:
Fangchinoline

[Synonym ]:
Berbaman-7-ol, 6,6',12-trimethoxy-2,2'-dimethyl-
Fangquinoline
FF-0018
d,l-Fangchinolin
(S,S)-(+)-tetrandine
12-O-MethylatherosperMoline
(1β)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol
Tetrandrine B
6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol
Hanfangichin B
N1799
I06-1344
THALRUGOSINE
Fangchinoline
7-o-demethyltetrandrine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
709.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C37H40N2O6

[ Molecular Weight ]:
608.723

[ Flash Point ]:
383.0±32.9 °C

[ Exact Mass ]:
608.288635

[ PSA ]:
72.86000

[ LogP ]:
3.78

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.602

[ Storage condition ]:
2-8C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DR9280000
CHEMICAL NAME :
Berbaman-7-ol, 2,2'-dimethyl-6,6',12-trimethoxy-, (1-beta)-
CAS REGISTRY NUMBER :
436-77-1
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C37-H40-N2-O6
MOLECULAR WEIGHT :
608.79

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 24,2413,1976

Synthetic Route

Precursor & DownStream

Precursor

  • Tetrandrine

DownStream

  • Isotetrandrine
  • Fangchinoline 7-acetate

Related Compounds

  • Fangchinoline
  • 7-O-Ethylfangchinoline
  • Fangchinoline 7-acetate
  • 7-O-isopropyl fangchinoline