3-(DIETHYLAMINO)PROPYL CINNAMATE

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Names

[ CAS No. ]:
4361-80-2

[ Name ]:
3-(DIETHYLAMINO)PROPYL CINNAMATE

[Synonym ]:
3-(DIETHYLAMINO)PROPYL CINNAMATE
Cinnamicacid,3-(diethylamino)propyl ester (8CI)
1-Propanol,3-(diethylamino)-,cinnamate (ester)
2-Propenoic acid,3-phenyl-,3-(diethylamino)propyl ester
Apothesine

Chemical & Physical Properties

[ Density]:
1.018g/cm3

[ Boiling Point ]:
378.5ºC at 760 mmHg

[ Melting Point ]:
137ºC (ethanol ethyl ether )

[ Molecular Formula ]:
C16H23NO2

[ Molecular Weight ]:
261.35900

[ Flash Point ]:
127.8ºC

[ Exact Mass ]:
261.17300

[ PSA ]:
29.54000

[ LogP ]:
2.97490

[ Index of Refraction ]:
1.536

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GD8900000
CHEMICAL NAME :
Cinnamic acid, 3-(diethylamino)propyl ester
CAS REGISTRY NUMBER :
4361-80-2
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C16-H23-N-O2
MOLECULAR WEIGHT :
261.40
WISWESSER LINE NOTATION :
2N2&3OV1U1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 68,110,1924
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 11,1082,1926
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 11,1082,1926
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898- Volume(issue)/page/year: 68,110,1924
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
37 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 22,375,1924
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 11,1082,1926

Safety Information

[ HS Code ]:
2922199090

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • 3-(diethylamino)propyl 3,5-dimethylbenzoate
  • 3-(diethylamino)propyl 2,2-diphenylacetate,hydrochloride
  • 3-(diethylamino)propyl 2-hydroxy-2,2-diphenylacetate,hydrochloride
  • 3-(diethylamino)propyl 3-methyl-2-thiophen-2-ylpentanoate,hydrochloride
  • 3-(diethylamino)propyl 2-methylprop-2-enoate
  • 3-(diethylamino)propyl prop-2-enoate
  • 3-(2-Methylbenzimidazol-1-yl)pyridine-2-carbonitrile
  • 4-(4-(6-Methyl-1H-indazol-3-yl)pyridin-2-yl)morpholine
  • 1,1,2,2,3,3,4,4,5,5,6,6-Dodecafluoro-1,8-diiodo-octane
  • 4b,5,6,7,8,8a,9,10-Octahydro-10-oxo-2-phenanthreneacetic acid
  • 6-Ethyl-5-oxo-4,5-dihydropyrazine-2-carboxylic acid
  • methyl 2-[(1Z)-3,3,5-trimethylcyclohexylidene]acetate
  • 2-Chloro-3,3-dimethylcyclopent-1-ene-1-carbaldehyde
  • 1-[[1-(4-Nitrophenyl)piperidin-4-yl]amino]propan-2-ol
  • 2-{[(Tert-butoxy)carbonyl]amino}-5-methyl-4-oxoheptanoic acid
  • 2,5-Difluorophenyl chloroformate
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