2,5-Cyclohexadiene-1,4-dione,2,3-dimethoxy-5-methyl-6-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-

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Names

[ Name ]:
2,5-Cyclohexadiene-1,4-dione,2,3-dimethoxy-5-methyl-6-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-

[Synonym ]:
Ubiquinone-4
2,3-Dimethoxy-5-methyl-6-geranyl-geranyl-benzo-1,4-chinon
Coenzyme Q4
2,3-Dimethoxy-5-methyl-6-(geranylgeranyl)-1,4-benzoquinone Q-4 Ubiquinone-20 Ubiquinone-4
Q-4
Ubiquinone Q4
All-Trans Coenzyme Q4
COENZYME Q4

Chemical & Physical Properties

[ Density]:
1.01g/cm3

[ Boiling Point ]:
584.1ºC at 760mmHg

[ Molecular Formula ]:
C₂₉H₄₂O₄

[ Molecular Weight ]:
454.64

[ Flash Point ]:
244.8ºC

[ Exact Mass ]:
454.30800

[ PSA ]:
52.60000

[ LogP ]:
7.49490

[ Index of Refraction ]:
1.507

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

trimethylaluminum
1-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]-6-methyl-2,3,4,5-tetramethoxybenzene
(E)-1-((3,7-dimethylocta-2,6-dien-1-yl)sulfonyl)-4-methylbenzene
(2'E)-1-(3,7-dimethylocta-2,6-dienyl)-6-methyl-2,3,4,5-tetramethoxybenzene
(E)-2,6-dimethyl-8-(2,3,4,5-tetramethoxy-6-methylphenyl)octa-1,6-dien-3-ol

DownStream

Articles

A Drosophila model for primary coenzyme Q deficiency and dietary rescue in the developing nervous system.

Dis. Model Mech. 3 , 799-806, (2010)

Coenzyme Q (CoQ) or ubiquinone is a lipid component of the electron transport chain required for ATP generation in mitochondria. Mutations in CoQ biosynthetic genes are associated with rare but severe...

Antioxidant action of ubiquinol homologues with different isoprenoid chain length in biomembranes.

Free Radic. Biol. Med. 9 , 117-126, (1990)

Ubiquinones (CoQn) are intrinsic lipid components of many membranes. Besides their role in electron-transfer reactions they may act as free radical scavengers, yet their antioxidant function has recei...

Bioenergetics in clinical medicine: prevention by forms of coenzyme Q of the inhibition by adriamycin of coenzyme Q10-enzymes in mitochondria of the myocardium.

Proc. Natl. Acad. Sci. U. S. A. 73 , 4653-4656, (1976)

Adriamycin inhibits the succinoxidase system and the NADH-oxidase system. Both of the intact mitocondrial enzymes and the pentane-extracted preparations are inhibited. The inhibition can be prevented ...

1,1-Dimethylethyl 2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethylidene]hydrazinecarboxylate
2-[(2-Methyl-1-oxo-2-propen-1-yl)oxy]ethyl 13-methyl-10-oxo-11-oxa-2,9,12-triazapentadec-12-enoate
6-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1-methyl-4(1H)-quinolinone
Ethyl 4-[(1-methyl-2-phenylethyl)amino]-2-butenoate
2-Quinolinemethanamine, I+/--methyl-I+/--(1-methylethyl)-
Hexahydro-I(2)-methyl-2-oxo-1H-azepine-1-propanamide
2H-1-Benzopyran-5-carboxylic acid, 8-cyano-3,4-dihydro-4-oxo-, methyl ester
3,7-Dihydro-1,3,8-trimethyl-7-[(phenylmethylene)amino]-1H-purine-2,6-dione
2-Diazo-1-(2-methoxy-6-methylphenyl)ethanone
2,3-Dihydro-1-methyl-2-oxo-3-(phenylmethyl)-1H-imidazole-4-carboxylic acid

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