Estrone sulfate sodium

Suppliers

Names

[ CAS No. ]:
438-67-5

[ Name ]:
Estrone sulfate sodium

[Synonym ]:
Estra-1(10),2,4-trien-17-one, 3-(sulfooxy)-, sodium salt (1:1)
Sodium 17-oxoestra-1(10),2,4-trien-3-yl sulfate
Estrone 3-sulfate sodium salt
Estrone sodium sulfate
Estrone sulfate sodium
Estrone-3-sulfate sodium salt
estrone sodium sulphate
Sodium estrone 3-sulfate

Chemical & Physical Properties

[ Density]:
1.349 g/cm3

[ Melting Point ]:
258-260°C

[ Molecular Formula ]:
C18H21NaO5S

[ Molecular Weight ]:
372.41

[ Exact Mass ]:
372.100739

[ PSA ]:
91.88000

[ LogP ]:
4.03160

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KG8775000
CHEMICAL NAME :
Estrone, hydrogen sulfate, sodium salt
CAS REGISTRY NUMBER :
438-67-5
LAST UPDATED :
199509
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H22-O5-S.Na
MOLECULAR WEIGHT :
373.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
504 ug/kg
SEX/DURATION :
female 9 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 55,191,1979

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H335-H350

[ Precautionary Statements ]:
P201-P261-P305 + P351 + P338-P308 + P313

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R45-36/37/38

[ Safety Phrases ]:
S53-45-26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
KG8775000

Precursor & DownStream

Precursor

  • estrone neopentyl sulfate
  • Estrone

DownStream

  • Estrone

Articles

Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.

J. Pharm. Sci. 102(1) , 280-8, (2013)

We aimed to explore the major active components in grapefruit juice (GFJ), orange juice (OJ), and apple juice (AJ) that are responsible for OATP2B1-mediated drug interactions, by means of in vitro stu...

Quantitative transporter proteomics by liquid chromatography with tandem mass spectrometry: addressing methodologic issues of plasma membrane isolation and expression-activity relationship.

Drug Metab. Dispos. 43(2) , 284-8, (2015)

To predict transporter-mediated drug disposition using physiologically based pharmacokinetic models, one approach is to measure transport activity and relate it to protein expression levels in cell li...

Inclusion of endogenous hormone levels in risk prediction models of postmenopausal breast cancer.

J. Clin. Oncol. 32(28) , 3111-7, (2014)

Endogenous hormones are risk factors for postmenopausal breast cancer, and their measurement may improve our ability to identify high-risk women. Therefore, we evaluated whether inclusion of plasma es...


More Articles

Related Compounds

  • ESTRONE SULFATE SODIUM
  • Estrone sulfate-d4 sodium
  • Estrone sulfate potassium
  • glucosamine sulfate sodium chloride
  • CHOLECALCIFEROL SULFATE SODIUM
  • Dehydroepiandrosterone sulfate sodium salt
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • Amiodarone metabolite M9
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide