Carboxyethyl-γ-aminobutyric acid

Names

[ CAS No. ]:
4386-03-2

[ Name ]:
Carboxyethyl-γ-aminobutyric acid

[Synonym ]:
4-(2-carboxyethylamino)butanoic acid

Chemical & Physical Properties

[ Density]:
1.232g/cm3

[ Boiling Point ]:
409.2ºC at 760mmHg

[ Molecular Formula ]:
C7H13NO4

[ Molecular Weight ]:
175.18200

[ Flash Point ]:
201.3ºC

[ Exact Mass ]:
175.08400

[ PSA ]:
86.63000

[ LogP ]:
0.30640

[ Index of Refraction ]:
1.491

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK7730000
CHEMICAL NAME :
Butanoic acid, 4-((2-carboxyethyl)amino)-
CAS REGISTRY NUMBER :
4386-03-2
BEILSTEIN REFERENCE NO. :
1774240
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H13-N-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
877 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJBIAC Italian Journal of Biochemistry. (I1 Pensiero Scientifico Editore, Via Panama 48, I-00198 Rome, Italy) V.1- 1957- Volume(issue)/page/year: 33,31A,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
783 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJBIAC Italian Journal of Biochemistry. (I1 Pensiero Scientifico Editore, Via Panama 48, I-00198 Rome, Italy) V.1- 1957- Volume(issue)/page/year: 33,31A,1984

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
EK7730000

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(2-oxopiperidin-1-yl)propanoic acid

DownStream

  • 3-(2-OXO-PYRROLIDIN-1-YL)-PROPIONIC ACID

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Carboxyethyl gamma-aminobutyric acid, a polyamine derivative molecule with a growth effect on hybridomas.

J. Immunol. Methods 77 , 229, (1985)

An increased proliferation of hybridomas is induced by a polyamine derivative molecule, CEGABA (carboxyethyl gamma-aminobutyric acid). The effects of CEGABA and CR-ECGS (endothelial cell growth supple...

Experimental study on central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA).

Farmaco. Sci. 43(4) , 363-72, (1988)

The central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA) have been studied both in rabbits and in the guinea pig myoclonus model. This drug caused EEG synchronization and behavioural sedat...

Identification of N-carboxyethyl gamma-aminobutyric acid in bovine brain and human cerebrospinal fluid.

Neurosci. Lett. 77(3) , 308-10, (1987)

The di-carboxylated derivative of spermidine, N-carboxyethyl gamma-aminobutyric acid (CEGABA) has been identified in bovine brain and human cerebrospinal fluid by HPLC. This discovery strongly suggest...


More Articles

Related Compounds

  • Trt-γ-aminobutyric acid
  • N-Arachidonoyl-γ-aminobutyric acid
  • N-(Trifluoroacetyl)-γ-aminobutyric Acid Chloride
  • N-phenyl-γ-aminobutyric acid hydrochloride
  • N-benzyl oxycarbonyl-γ-aminobutyric acid
  • N-α-Pyridylcarbonyl-γ-aminobutyric acid
  • 5,6-dichloro-N-{2,6-dioxaspiro[4.5]decan-9-yl}-2-methylpyridine-3-carboxamide
  • 4-methoxy-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)aniline
  • 3'-Methoxybiphenyl-4-boronic acid pinacol ester
  • 2-Chloro-5,6,7,8-tetrahydroquinoline-3-sulfonyl chloride
  • 5-Chloro-1,3-dihydro-3-oxo-2,1-benzisoxazole-4-carboxylic acid
  • [(3Ar,6aS)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl]-(2-fluorophenyl)methanone;hydrochloride
  • 2,5-dichloro-N-[1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl]pyridine-4-carboxamide
  • 2-[(2,5-Diamino-6-methyl-4-pyrimidinyl)thio]acetic acid
  • Rel-(3R,4R)-N-methyl-4-((1-methyl-1H-pyrazol-4-yl)oxy)tetrahydrofuran-3-amine
  • Methyl 5-chloro-6-(trifluoromethyl)pyridine-3-carboxylate
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