sodium barbiturate

Names

[ Name ]:
sodium barbiturate

[Synonym ]:
barbituric acid,sodium-salt
Barbituric acid sodium
barbituricacid,monosodiumsalt
2,4,6(1H,2H,5H)-Pyrimidinetrione,monosodiumsalt
2,4,6(1h,3h,5h)-pyrimidinetrione,monosodiumsalt
monosodiumbarbiturate
2-Sodiooxy-4,6(1H,5H)-pyrimidinedione
2,4,6(1H,3H,5H)-Pyrimidinetrione,sodium salt (1:1)
Barbitursaeure,Natrium-Salz

Chemical & Physical Properties

[ Density]:
1.455g/cm3

[ Molecular Formula ]:
C₄H₃N₂NaO₃

[ Molecular Weight ]:
150.06800

[ Exact Mass ]:
150.00400

[ PSA ]:
81.59000

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CQ7280000

CHEMICAL NAME :: Barbituric acid, monosodium salt

CAS REGISTRY NUMBER :: 4390-16-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-H4-N2-O3.Na

MOLECULAR WEIGHT :: 151.09

WISWESSER LINE NOTATION :: T6VMVMV FHJ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14 gm/kg/20W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors

REFERENCE :: JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 63,1089,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84244 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 41 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84244 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 14 (estimated) No. of Female Employees: 14 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CQ7280000

[ HS Code ]:
2933540000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933540000

[ Summary ]:
2933540000 other derivatives of malonylurea (barbituric acid); salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:20.0%

Articles

Identification and characterization of Clostridium perfringens beta toxin variants with differing trypsin sensitivity and in vitro cytotoxicity activity.

Infect. Immun. 83(4) , 1477-86, (2015)

By producing toxins, Clostridium perfringens causes devastating diseases of both humans and animals. C. perfringens beta toxin (CPB) is the major virulence determinant for type C infections and is als...

Characterization of two long-chain fatty acid CoA ligases in the Gram-positive bacterium Geobacillus thermodenitrificans NG80-2.

Microbiol. Res. 167(10) , 602-7, (2012)

The functions of two long-chain fatty acid CoA ligase genes (facl) in crude oil-degrading Geobacillus thermodenitrificans NG80-2 were characterized. Facl1 and Facl2 encoded by GTNG_0892 and GTNG_1447 ...

Synergistic effects of Clostridium perfringens enterotoxin and beta toxin in rabbit small intestinal loops.

Infect. Immun. 82(7) , 2958-70, (2014)

The ability of Clostridium perfringens type C to cause human enteritis necroticans (EN) is attributed to beta toxin (CPB). However, many EN strains also express C. perfringens enterotoxin (CPE), sugge...

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