Bromocyclobutane

Names

[ CAS No. ]:
4399-47-7

[ Name ]:
Bromocyclobutane

[Synonym ]:
Cyclobutane, bromo-
EINECS 224-530-9
MFCD00001317
Bromocyclobutane
Cyclobutyl bromide

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
107.1±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₇Br

[ Molecular Weight ]:
135.002

[ Flash Point ]:
22.2±0.0 °C

[ Exact Mass ]:
133.973099

[ LogP ]:
2.08

[ Vapour Pressure ]:
32.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.527

[ Storage condition ]:
0-6°C

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R10;R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S16

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2903890090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

cyclobutane carboxylic acid silver salt
(Chloromethyl)cyclopropane
But-2-yne
1,1-dibromocyclobutane
1,1-Dichlorocyclobutane
Cyclobutanol
Cyclopropyl carbinol
Cyclo-butyl formic acid
NORBORNENE
Hydrogen bromide

DownStream

bromoethene
ethene
butadiene
4-Brombut-1-en
Cyclobutanesulfonyl chloride
Cyclobutyl(phenyl)methanone
9-cyclobutylpurin-6-amine
3-Cyclobutoxy-4-difluoromethoxy-benzaldehyde
cyclobutyl(trimethyl)silane
cyclobutyl phenylsulfide

Customs

[ HS Code ]: 2903890090

[ Summary ]:
2903890090. halogenated derivatives of cyclanic, cyclenic or cyclotherpenic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3.

J. Med. Chem. 48 , 6169, (2005)

A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and S1P3 receptor subtypes...

Photodissociation of cyclobutyl bromide at 234 nm studied using velocity map imaging.

J. Phys. Chem. A 110(16) , 5379-85, (2006)

This study investigates the 234 nm photodissociation dynamics of cyclobutyl bromide using a two-dimensional photofragment velocity imaging technique. The spin-orbit ground- and excited-state Br(2P) at...

Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis.

Bioorg. Med. Chem. Lett. 15 , 3696, (2005)

An encoded combinatorial library based on aryl and biaryl piperidine scaffolds was designed and synthesized. Screening of this library resulted in the discovery of high-nanomolar biaryl piperidine-bas...

1-bromocyclobutanecarboxamide
1-Bromocyclobutanecarboxylic acid
Ethyl 1-bromocyclobutanecarboxylate
Ethyl 3-bromocyclobutanecarboxylate
Methyl 1-Bromocyclobutanecarboxylate
methyl 3-bromocyclobutane-1-carboxylate
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
N-(5-allyl-3,3-dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)-3,5-dimethylbenzamide
3-(Chloromethyl)-5-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,2,4-oxadiazole
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine