WAY 200070

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Names

[ CAS No. ]:
440122-66-7

[ Name ]:
WAY 200070

[Synonym ]:
7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol
5-Benzoxazolol,7-bromo-2-(4-hydroxyphenyl)
7-BROMO-2-(4-HYDROXYPHENYL)-1,3-BENZOXAZOL-5-OL
7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol 7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol
7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol
WAY-200070

Chemical & Physical Properties

[ Molecular Formula ]:
C13H8BrNO3

[ Molecular Weight ]:
306.11200

[ Exact Mass ]:
304.96900

[ PSA ]:
66.49000

[ LogP ]:
3.66850

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H319

[ Precautionary Statements ]:
P301 + P310-P305 + P351 + P338

[ RIDADR ]:
UN 2811 6.1 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 7-bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole
  • 4-Methoxy-2-nitrophenol

DownStream

Articles

Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity.

Breast Cancer Res. 13(2) , R43, (2011)

The inhibition of estrogen receptor (ER) α action with the ER antagonist tamoxifen is an established treatment in the majority of breast cancers. De novo or acquired resistance to this therapy is comm...

Antidiabetic actions of an estrogen receptor β selective agonist.

Diabetes 62(6) , 2015-25, (2013)

The estrogen receptor β (ERβ) is emerging as an important player in the physiology of the endocrine pancreas. We evaluated the role and antidiabetic actions of the ERβ selective agonist WAY200070 as a...

Effects of an estrogen receptor alpha agonist on agonistic behaviour in intact and gonadectomized male and female mice.

Psychoneuroendocrinology 36(7) , 981-95, (2011)

Gonadal hormones mediate both affiliative and agonistic social interactions. Research in estrogen receptor alpha (ERα) or beta (ERβ) knockout (KO) mice suggests that ERα increases and ERβ decreases ma...


More Articles

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