4-Hydroxy-3-Methoxybenzonitrile

Names

[ Name ]:
4-Hydroxy-3-Methoxybenzonitrile

[Synonym ]:
4-Hydroxy-3-methoxybenzonitrile
m-anisonitrile, 4-hydroxy-
Vanillonitrile
Benzonitrile, 4-hydroxy-3-methoxy-
MFCD00001820
EINECS 224-589-0

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
291.6±30.0 °C at 760 mmHg

[ Melting Point ]:
85-87 °C(lit.)

[ Molecular Formula ]:
C₈H₇NO₂

[ Molecular Weight ]:
149.147

[ Flash Point ]:
130.1±24.6 °C

[ Exact Mass ]:
149.047684

[ PSA ]:
53.25000

[ LogP ]:
1.18

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.569

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S37/39-S36/37/39

[ RIDADR ]:
3439

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Naravelia zeylanica [corrected] occurrence of primary benzamides in flowering plants.

Nat. Prod. Res. 19(3) , 291-4, (2005)

Extract of Naravelia zeylanica (Ranunculaceae) yielded three simple benzamides, 3,4-methylenedioxybenzamide, 4-methoxybenzamide and 4-hydroxy-3-methoxybenzamide. These simple C6C1 metabolites have bee...

Analogs of pentamidine as potential anti-Pneumocystis chemotherapeutics.

Eur. J. Med. Chem. 48 , 164-73, (2012)

A series of 20 pentamidine analogs were prepared using 2 general Schemes that evaluated heteroatoms, sulfobenzene and alkanediamide groups in the aliphatic linker and methoxy substituents attached to ...

4-hydroxy-3,7-dimethylinden-1-one
4-Hydroxy-3,5-diisopropylbenzylalkohol
4-hydroxy-3-methyl-4-phenyl-thiolan-2-one
4-hydroxy-3-methyl-6-propan-2-ylcyclohex-2-en-1-one
4-Hydroxy-3,5-diiodopyridine-2-carboxylic acid
4-Hydroxy-3-(3-methylphenyl)-1,8-naphthyridin-2(1H)-one
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
5-Methyl-4-(1H-pyrazol-1-yl)thiazol-2-amine
2-(3-((2-((4-ethoxyphenyl)amino)-2-oxoethyl)sulfonyl)-1H-indol-1-yl)-N,N-diisopropylacetamide
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine