CK 666

Suppliers

Names

[ CAS No. ]:
442633-00-3

[ Name ]:
CK 666

[Synonym ]:
2-fluoro-N-(2-(2-methyl-1H-indol-3-yl)ethyl)benzamide
CK-666

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₇FN₂O

[ Molecular Weight ]:
296.33900

[ Exact Mass ]:
296.13200

[ PSA ]:
48.38000

[ LogP ]:
4.16270

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Methylindole-3-ethylamine
2-Fluorobenzoyl chloride
2-Methylindole
2-Methyl-1H-indole-3-carbaldehyde
(E)-2-methyl-3-(2-nitrovinyl)-1H-indole

DownStream

Articles

Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling.

J. Cell Sci. 128 , 3781-95, (2015)

Many important signalling cascades operate through specialized signalling endosomes, but a corresponding mechanism has as yet not been described for hematopoietic cytokine receptors. Based on live-cel...

Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy.

Nat. Commun. 6 , 8045, (2015)

Autophagy is an important degradation pathway, which is induced after starvation, where it buffers nutrient deprivation by recycling macromolecules in organisms from yeast to man. While the classical ...

PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions.

J. Cell Biol. 210 , 753-69, (2015)

Branched actin critically contributes to membrane trafficking by regulating membrane curvature, dynamics, fission, and transport. However, how actin dynamics are controlled at membranes is poorly unde...

CK-2127107
CK-0106023
CK-636
CK 204-933
ck 53
CK-37
(2S)-4-bromobutan-2-amine
2-({Amino[(3-methoxybenzyl)sulfanyl]methylene}amino)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidine
Methyl 4,4-dimethyl-3-({[3-(trifluoromethyl)phenyl]methyl}amino)pentanoate
4-Methyl-3-({[3-(trifluoromethyl)phenyl]methyl}amino)pentanoic acid
Ethyl 4-methyl-3-({[3-(trifluoromethyl)phenyl]methyl}amino)pentanoate
3-Bromo-2-chloro-6-iodobenzoic acid
2-(2-Bromopropanoyl)-4-fluorobenzonitrile
2-Methyl-3-(1-methylcyclohexyl)propanoic acid
Benzoic acid, 2,3-diiodo-6-methoxy-, methyl ester
(S)-1-(3-Bromo-5-methylphenyl)butan-1-amine

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