MES

Suppliers

Names

[ Name ]:
MES

[Synonym ]:
MES HYDRAT
2-Morpholinoethanesulfonic acid
MES ANHYDROUS
2-(morpholin-4-yl)ethanesulfonic acid
MES,ULTRAPURE
mes solution
2-(N-Morpholino)ethanesulfonic acid
MOPS solution
MFCD00006181
morpholino ethane sulfonic acid
MES hydrate
2-(N-Morpholino)ethanesulfonic acid (MES)
surfactant MES
2-(4-Morpholinyl)ethanesulfonic acid
2-(4-Morpholino)ethanesulfonic acid
MES
4-Morpholineethanesulfonic acid
2-(N-Morpholino)ethanesulfonic acid,4-Morpholineethanesulfonic acid
EINECS 224-632-3

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C₆H₁₃NO₄S

[ Molecular Weight ]:
195.237

[ Exact Mass ]:
195.056534

[ PSA ]:
75.22000

[ LogP ]:
-2.13

[ Index of Refraction ]:
1.517

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
H2O: 0.5 M at 20 °C, clear

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QE3479500

CHEMICAL NAME :: 4-Morpholineethanesulfonic acid

CAS REGISTRY NUMBER :: 4432-31-9

BEILSTEIN REFERENCE NO. :: 0141319

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H13-N-O4-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6845 No. of Facilities: 257 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 5949 (estimated) No. of Female Employees: 4797 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36-S24/25-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
QE9104530

[ HS Code ]:
29349990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.

Cancer Chemother. Pharmacol. 75(2) , 431-7, (2015)

2-Methoxyestradiol (2ME) is a promising anti-cancer agent that disrupts the integrity and dynamics of the spindle network. In order to overcome the pharmacokinetic constraints of this compound, a pane...

Crystals of Na(+)/K(+)-ATPase with bound cisplatin.

Biochem. Pharmacol. 92(3) , 494-8, (2014)

Cisplatin is the most widely used chemotherapeutics for cancer treatment, however, its administration is connected to inevitable adverse effects. Previous studies suggested that cisplatin is able to i...

Stability of collapse lyophilized influenza vaccine formulations.

Int. J. Pharm. 483(1-2) , 131-41, (2015)

A clear limitation of many liquid vaccines is the obligatory cold-chain distribution system. Therefore, distribution of a dried vaccine formulation may be beneficial in terms of vaccine stability, han...

MES