ALPHA-THYMIDINE

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Names

[ CAS No. ]:
4449-43-8

[ Name ]:
ALPHA-THYMIDINE

[Synonym ]:
L-Dt
MFCD00069766
L-2'-deoxythymidine
Epavudine
2'-DEOXY-L-THYMIDINE
NV 02B
L-Deoxythymidine

Chemical & Physical Properties

[ Density]:
1.452g/cm3

[ Molecular Formula ]:
C10H14N2O5

[ Molecular Weight ]:
242.22900

[ Exact Mass ]:
242.09000

[ PSA ]:
104.55000

[ Index of Refraction ]:
1.584

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

Bioorg. Med. Chem. 19(24) , 7603-1, (2011)

We report on Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitory activities of a series of new 3'- and 5'-modified thymidine analogues including α- and β-derivatives. In addi...

Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.

J. Chem. Inf. Model. 49 , 1070-1078, (2009)

Thymidine monophosphate kinase (TMPK) has emerged as an attractive target for developing inhibitors of Mycobacterium tuberculosis growth. In this study the receptor-independent (RI) 4D-QSAR formalism ...

Chemical synthesis of hydroxymethylphosphonate alpha-DNA.

Nucleic Acids Symp. Ser. 44 , 31-32, (2000)

In this paper, we report the synthesis of hydroxymethylphosphonate alpha-DNAs and related compounds by use of the H-phosphonate method. These modified alpha-DNAs were designed to improve the inherent ...


More Articles

Related Compounds

  • alpha-(3-(1,1-Dimethylethyl)-2-hydroxyphenyl)-1-methyl-5-nitro-1H-imidazole-2-methanol
  • alpha-d-Glucopyranoside, beta-d-fructofuranosyl, (Z,Z)-9,12-octadecadienoate
  • alpha,gamma,4-trimethylcyclohex-3-ene-1-butyraldehyde
  • alpha-monofluoromethyl-beta-(2,3-dihydroxyphenyl)alanine
  • alpha-(4-ethylphenylimino)-p-cresol
  • alpha-(3,4-dimethoxyphenethylimino)-alpha-methyl-o-cresol
  • 2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoyl]-2-azabicyclo[4.1.0]heptane-1-carboxylic acid
  • 1-[2-cyclobutyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetyl]-3-ethylpyrrolidine-3-carboxylic acid
  • 1-[2-cyclobutyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetyl]-4-methylpiperidine-4-carboxylic acid
  • 1-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxane-4-carbonyl}-3-methylazetidine-3-carboxylic acid
  • 1-[(3S)-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-5-methylhexanoyl]-3-methylazetidine-3-carboxylic acid
  • 1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5,5-dimethylhexanoyl]-3-methylazetidine-3-carboxylic acid
  • 1-[4-ethyl-6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoyl]-3-methylazetidine-3-carboxylic acid
  • 1-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4,4-dimethylpentanoyl}-3-methylazetidine-3-carboxylic acid
  • 1-{2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1,3-thiazole-4-carbonyl}-3-methylazetidine-3-carboxylic acid
  • 1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-iodobenzoyl]-3-methylazetidine-3-carboxylic acid
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