2-Bromo-5-nitropyridine

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Names

[ CAS No. ]:
4487-59-6

[ Name ]:
2-Bromo-5-nitropyridine

[Synonym ]:
2-bromo-5-(nitro)pyridine
5-nitro-2-bromopyridine
MFCD00006222
Pyridine, 2-bromo-5-nitro-
2-brom-5-nitropyridin
2-Bromo-5-nitropyridine
3-Nitro-6-bromopyridine
2-bromo-5-nitroypyridine
2-Bromo-5-Nitro pyridine
EINECS 224-777-2

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
289.3±0.0 °C at 760 mmHg

[ Melting Point ]:
139-141 °C(lit.)

[ Molecular Formula ]:
C5H3BrN2O2

[ Molecular Weight ]:
202.99

[ Flash Point ]:
122.2±21.8 °C

[ Exact Mass ]:
201.937775

[ PSA ]:
58.71000

[ LogP ]:
1.20

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
Keep Cold

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S37/39-S22

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-nitropyridin-2-ol
  • 5-Nitro-2-pyridinamine
  • BPBA

DownStream

  • 5-Iodopicolinic acid
  • 5-Nitropyridine-2-carboxamide
  • 5-Bromo-2-pyridinecarboxylic acid
  • N-(4-methoxyphenyl)-5-nitropyridin-2-amine
  • 3-Aminopyridine
  • 2-methylamino-5-nitropyridine
  • 5-Nitro-2-pyridinamine
  • methyl 4-(5-nitropyridin-2-yl)benzoate
  • 5-NITRO-2-METHYLTHIOPYRIDINE
  • tert-Butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis of a (piperazin-1-ylmethyl) biaryl library via microwave-mediated Suzuki-Miyaura cross-couplings. Spencer J, et al.

Tetrahedron Lett. 52(31) , 3963-68, (2011)

Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.

Bioorg. Med. Chem. Lett. 21(19) , 5812-7, (2011)

The diacylglycerol acyltransferase enzyme, DGAT1, presents itself as a potential target for obesity as this enzyme is dedicated to the final committed step in triglyceride biosynthesis. Biphenyl ureas...


More Articles

Related Compounds

  • 2-Bromo-5-nitropyridine
  • 2-Bromo-5-nitropyridine1-oxide
  • 6-amino-2-bromo-5-nitropyridine
  • 2-bromo-5-nitropyridine-4-carboxylic acid
  • 2-bromo-5-nitropyridine-3-carboxylic acid
  • 2-Bromo-5-fluoro-4-nitropyridine
  • Methyl 2-cyclopropanecarbonyl-5-methoxy-5-methyl-4-oxohexanoate
  • O-{[1-(2,6-dimethoxy-4-methylphenyl)cyclopropyl]methyl}hydroxylamine
  • 4-{[1-(Aminomethyl)cyclopropyl]methyl}-5-bromo-2-methoxyphenol
  • (1S)-2,2,2-trifluoro-1-[4-methoxy-3-(trifluoromethyl)phenyl]ethan-1-ol
  • N-methyl-N-[3-(1H-1,2,3,4-tetrazol-1-yl)propyl]hydroxylamine
  • methyl 4-(3-amino-1-fluoropropyl)-1-methyl-1H-pyrrole-2-carboxylate
  • 3-(4-Bromo-3-methoxyphenyl)-1,1-difluoropropan-2-amine
  • rac-[(1R,2R)-2-(5-bromo-2-cyclopropylpyrimidin-4-yl)cyclopropyl]methanamine
  • 1-(1-Benzylpyrrolidin-2-yl)cyclohexan-1-amine
  • (1R)-2,2,2-trifluoro-1-(1,2-oxazol-3-yl)ethan-1-ol
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