R1487

Suppliers

Names

[ CAS No. ]:
449811-92-1

[ Name ]:
R1487

[Synonym ]:
6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidine-7-one
[14C]-R1487
6-(2,4-Difluorophenoxy)-2-{[3-Hydroxy-1-(2-Hydroxyethyl)propyl]amino}-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One
6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
Pamapimod (INN/USAN)
Pamapimod
[14C]-Pamapimod
6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
R1487

Chemical & Physical Properties

[ Molecular Formula ]:
C19H18F2N4O3

[ Molecular Weight ]:
388.36800

[ Exact Mass ]:
388.13500

[ PSA ]:
81.50000

[ LogP ]:
2.41180

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Aminotetrahydropyran
  • 6-(2,4-Difluorophenoxy)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one
  • (4-(Methylamino)-2-(methylthio)pyrimidin-5-yl)methanol
  • Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate
  • 4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
  • 4-methylamino-2-methylsulfanyl-pyrimidine-5-carbaldehyde

DownStream

Related Compounds

  • R1487 HCl
  • Tert-butyl 4-(4-bromo-3-fluorophenyl)-4-methoxypiperidine-1-carboxylate
  • tert-butyl 6'-bromo-5,6-dihydro-[3,3'-bipyridine]-1(2H)-carboxylate
  • 2-Bromo-5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridine
  • 4-(6-Bromopyrrolo[1,2-b]pyridazin-4-yl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
  • tert-butyl 3-(4-bromophenyl)-2,5-dihydro-1H-pyrrole-1-carboxylate
  • (E)-8-(2-(1-(2-hydroxyphenyl)ethylidene)hydrazinyl)-7-isobutyl-3-methyl-1H-purine-2,6(3H,7H)-dione
  • tert-butyl 6'-(benzyloxy)-5,6-dihydro-[3,3'-bipyridine]-1(2H)-carboxylate
  • tert-butyl 4-(4-bromo-3-chlorophenyl)-3,6-dihydropyridine-1(2H)-carboxylate
  • tert-butyl 4-(4-((tert-butoxycarbonyl)oxy)phenyl)-4-methyl-3,4-dihydropyridine-1(2H)-carboxylate
  • (E)-8-(2-(2,4-dihydroxybenzylidene)hydrazinyl)-7-isobutyl-3-methyl-1H-purine-2,6(3H,7H)-dione
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