R1487

Suppliers

Names

[ Name ]:
R1487

[Synonym ]:
6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidine-7-one
[14C]-R1487
6-(2,4-Difluorophenoxy)-2-{[3-Hydroxy-1-(2-Hydroxyethyl)propyl]amino}-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One
6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
Pamapimod (INN/USAN)
Pamapimod
[14C]-Pamapimod
6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
R1487

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₈F₂N₄O₃

[ Molecular Weight ]:
388.36800

[ Exact Mass ]:
388.13500

[ PSA ]:
81.50000

[ LogP ]:
2.41180

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Aminotetrahydropyran
6-(2,4-Difluorophenoxy)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one
(4-(Methylamino)-2-(methylthio)pyrimidin-5-yl)methanol
Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate
4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
4-methylamino-2-methylsulfanyl-pyrimidine-5-carbaldehyde