R1487

Suppliers

Names

[ CAS No. ]:
449811-92-1

[ Name ]:
R1487

[Synonym ]:
6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidine-7-one
[14C]-R1487
6-(2,4-Difluorophenoxy)-2-{[3-Hydroxy-1-(2-Hydroxyethyl)propyl]amino}-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One
6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
Pamapimod (INN/USAN)
Pamapimod
[14C]-Pamapimod
6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
R1487

Chemical & Physical Properties

[ Molecular Formula ]:
C19H18F2N4O3

[ Molecular Weight ]:
388.36800

[ Exact Mass ]:
388.13500

[ PSA ]:
81.50000

[ LogP ]:
2.41180

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Aminotetrahydropyran
  • 6-(2,4-Difluorophenoxy)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one
  • (4-(Methylamino)-2-(methylthio)pyrimidin-5-yl)methanol
  • Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate
  • 4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
  • 4-methylamino-2-methylsulfanyl-pyrimidine-5-carbaldehyde

DownStream

Related Compounds

  • R1487 HCl
  • 3-(2-aminoethyl)thieno[3,2-d][1,2,3]triazin-4(3H)-one
  • 5-Bromo-3-(piperazin-1-ylmethyl)benzo[d]isoxazole
  • 1-(1H-imidazol-2-yl)-1-(2-methoxyphenyl)ethan-1-ol
  • 5-(benzyloxy)-N,2-dimethylpyrimidin-4-amine
  • 5-(Benzyloxy)-2-methylpyrimidin-4-amine
  • 4-Bromo-3-methoxy-N-(2-methoxyethyl)benzamide
  • 4-(Dimethylamino)-2-methylpyrimidin-5-ol
  • 1-(5-(1H-pyrrol-1-yl)pyridin-2-yl)piperazine
  • 1-(6-Ethoxypyridazin-4-yl)piperidine-3-carboxylic acid
  • 1-Methyl-3-(4-oxocyclohexyl)imidazolidin-2-one
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