2,3-Diaminopyridine

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Names

[ CAS No. ]:
452-58-4

[ Name ]:
2,3-Diaminopyridine

[Synonym ]:
2,3-DiaMinopyridine
Pyridin-2,3-diamin
di-aminopyridine
Pyridin-2,3-diaMine
Diaminopyridine
Pyridine,2,3-diamino
1,2-pyridine diamine
EINECS 207-200-9
2,3-Pyridinediamine
2,3-diamino-pyridin
2,3-diamino-pyridine
3-DiaMinopyridine
MFCD00006319
Diaminopyridine (VAN)
pyridine-2,3-diamine
4-pyridinediamine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
311.3±22.0 °C at 760 mmHg

[ Melting Point ]:
110-115 °C(lit.)

[ Molecular Formula ]:
C₅H₇N₃

[ Molecular Weight ]:
109.129

[ Flash Point ]:
167.7±9.5 °C

[ Exact Mass ]:
109.063995

[ PSA ]:
64.93000

[ LogP ]:
0.27

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.676

[ Storage condition ]:
Refrigerator (+4°C)

[ Water Solubility ]:
100 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US7548000

CHEMICAL NAME :: Pyridine, 2,3-diamino-

CAS REGISTRY NUMBER :: 452-58-4

BEILSTEIN REFERENCE NO. :: 0109869

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H7-N3

MOLECULAR WEIGHT :: 109.15

WISWESSER LINE NOTATION :: T6NJ BZ CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,296,1965

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R25;R36/37/38

[ Safety Phrases ]:
S26-S36/37-S45-S37/39-S28A

[ RIDADR ]:
UN 2811

[ WGK Germany ]:
3

[ RTECS ]:
US7548000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-nitropyridin-2-amin
2-Hydrazino-3-nitropyridine
3,3'-dinitro-2,2'-hydrazobipyridine
N-benzyl-3-nitropyridin-2-amine
5-Brom-3-nitropyridin-2-amin
2-Chloro-3-nitropyridine
2-Nitro-3-pyridinamine
2-Amino-5-chloro-3-nitropyridine
2-Chlorpyridin-3-amin

DownStream

2-(3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)ACETONITRILE
2-isopropyl-1H-benzo[d]imidazole
Pyrido[2,3-b]pyrazine
2-(Benzylamino)-3-aminopyridine
2-nitro-3-benzylaminopyridine
N3-Benzyl-pyridine-2,3-diamine
2-N-ethylpyridine-2,3-diamine
2-phenyl-4H-pyrido[2,3-b]pyrazin-3-one
N2-methylpyridine-2,3-diamine
8-selena-2,7,9-triazabicyclo[4.3.0]nona-2,4,6,9-tetraene

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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