3-Fluoro-4-methylaniline

Suppliers

Names

[ CAS No. ]:
452-77-7

[ Name ]:
3-Fluoro-4-methylaniline

[Synonym ]:
3-FLUORO-PARA-TOLUIDINE
3-Fluoro-4-methylaniline
3-fluoro-4-methyl-benzenamin
3-fluoro-4-methyl-aniline
3-fluoro-p-toluidin
4-Amino-2-fluorotoluene
ZR CF D1
EINECS 207-212-4
3-Fluoro-4-methylani
3-Fluoro-p-toluidine
2-fluoro-4-aminotoluene
4-methyl-3-fluoroaniline
Benzenamine, 3-fluoro-4-methyl-
3-Fluoro-4-methylbenzenamine
MFCD00007762

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
203.8±20.0 °C at 760 mmHg

[ Melting Point ]:
30-32 °C

[ Molecular Formula ]:
C7H8FN

[ Molecular Weight ]:
125.144

[ Flash Point ]:
88.9±0.0 °C

[ Exact Mass ]:
125.064079

[ PSA ]:
26.02000

[ LogP ]:
1.85

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.542

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU6825000
CHEMICAL NAME :
p-Toluidine, 3-fluoro-
CAS REGISTRY NUMBER :
452-77-7
BEILSTEIN REFERENCE NO. :
2715987
LAST UPDATED :
199707
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H8-F-N
MOLECULAR WEIGHT :
125.16
WISWESSER LINE NOTATION :
ZR CF D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
1300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P264-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S45-S36/37/39-S26-S36/37

[ RIDADR ]:
2811

[ RTECS ]:
XU6825000

[ Packaging Group ]:
I

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2921430090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Fluoro-4-nitrotoluene
  • 2-Nitrotoluene
  • 3-fluoroaniline
  • Methyl fluoride
  • 4-CHLORO-2-FLUORO-1-METHYLBENZENE

DownStream

  • 2-Fluoro-4-methoxybenzoic acid
  • 3-Fluoro-4-methylphenol
  • 2-Fluoro-4-methoxy-1-methylbenzene
  • 4-Amino-2-fluorobenzoic acid
  • 3-Fluoro-4-methylbenzenethiol
  • 2-Fluoro-4-isocyanato-1-methylbenzene
  • 2-Bromo-5-fluoro-4-methylaniline
  • TERT-BUTYL 4-(BROMOMETHYL)-3-FLUOROPHENYLCARBAMATE
  • N-(3-Fluoro-4-methylphenyl)acetamide
  • tert-butyl N-(3-fluoro-4-methylphenyl)carbamate

Customs

[ HS Code ]: 2921430090

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Preconcentration of aniline derivatives from aqueous solutions using micellar-enhanced ultrafiltration.

Analyst 118(1) , 23-27, (1993)


More Articles

Related Compounds

  • N-Ethyl-3-fluoro-4-methylaniline
  • 2,6-Dibromo-3-fluoro-4-methylaniline
  • N-diethoxyphosphoryl-3-fluoro-4-methylaniline
  • N-diphenoxyphosphoryl-3-fluoro-4-methylaniline
  • 3-FLUORO-4-IODO-2-METHYLANILINE
  • 3-Fluoro-4-methoxy-2-methylaniline