1,2-Propanediol,3-fluoro-

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Names

[ CAS No. ]:
453-16-7

[ Name ]:
1,2-Propanediol,3-fluoro-

[Synonym ]:
MFCD00075515
1,2-Propanediol,3-fluoro-

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
205.4ºC at 760mmHg

[ Molecular Formula ]:
C3H7FO2

[ Molecular Weight ]:
94.08490

[ Flash Point ]:
87.2ºC

[ Exact Mass ]:
94.04300

[ PSA ]:
40.46000

[ Vapour Pressure ]:
0.0197mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.422(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TY6791500
CHEMICAL NAME :
1,2-Propanediol, 3-fluoro-
CAS REGISTRY NUMBER :
453-16-7
LAST UPDATED :
199007
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C3-H7-F-O2
MOLECULAR WEIGHT :
94.10
WISWESSER LINE NOTATION :
Q1YQ1F

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,644,1977

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H311-H315-H319-H331-H335

[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
23/24/25-36/37/38

[ Safety Phrases ]:
23-26-36/37/39-45

[ RIDADR ]:
UN 2810 6.1/PG 2

[ RTECS ]:
TY6791500

[ HS Code ]:
2905590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Epifluorohydrin
  • Glycidol
  • 4-fluoromethyl-2,2-dimethyl-[1,3]dioxolane
  • 3-Chloro-1,2-propanediol

DownStream

  • fluoroacetaldehyde
  • (2R)-3-fluoropropane-1,2-diol
  • (S)-3-Fluoropropane-1,2-Diol
  • Glycerophosphoric acid
  • Benzoic acid 3-fluoro-2-oxopropyl ester
  • 3-Fluoro-2-oxopropyl=p-nitrobenzoate
  • 3-Fluoro-2-hydroxypropyl=benzoate

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Related Compounds

  • 1,2-Propanediol,3-fluoro-,1-phosphate (ester),dicyclohexylammonium salt
  • 1,2-Propanediol,3-(dibutylamino)-
  • 1,2-Propanediol,3-propoxy-
  • 1,2-Propanediol,3-(octadecylsulfonyl)-
  • 1,2-Propanediol, 3-(p-(dimethylamino)phenoxy)-
  • 1,2-Propanediol, 3-(m-methoxyphenoxy)-