1,4-Diisocyanatobutane

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Names

[ CAS No. ]:
4538-37-8

[ Name ]:
1,4-Diisocyanatobutane

[Synonym ]:
1,4-Diisocyanatobutane
Butane, 1,4-diisocyanato-
1,4-bisisocyanatobutane
1,4-butanediisocyanate
1,4-diisocyanato-butane
1,4-tetramethylene diisocyanate
Butane,1,4-diisocyanato
Tetramethylene diisocyanate
butane-1,4-diisocyanate
MFCD00075559

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
220.5±0.0 °C at 760 mmHg

[ Melting Point ]:
0ºC

[ Molecular Formula ]:
C6H8N2O2

[ Molecular Weight ]:
140.140

[ Flash Point ]:
106.7±0.0 °C

[ Exact Mass ]:
140.058578

[ PSA ]:
58.86000

[ LogP ]:
2.27

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.484

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26-S27-S37-S39

[ RIDADR ]:
UN 2206

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
29291000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • phosgene
  • Adipoyl chloride
  • NN'-diformyl-1,4-diaminobutane
  • Hexanedioyl azide
  • putrescine
  • 1,4-Dichlorobutane

DownStream

  • N-(4-nitramidobutyl)nitramide
  • N,N'-Tetramethylenebis(1-aziridinecarboxamide)
  • 4-(carbamoylamino)butylurea

Articles

Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors.

Bioorg. Med. Chem. Lett. 24(9) , 2193-7, (2014)

A series of inhibitors of the soluble epoxide hydrolase (sEH) containing two urea groups has been developed. Inhibition potency of the described compounds ranges from 2.0 μM to 0.4 nM. 1,6-(Hexamethyl...


More Articles

Related Compounds

  • 1-[(4-Hydroxy-3,5-dimethylbenzoyl)oxy]-2,5-pyrrolidinedione
  • 1-(4-Aminobutyl)-4-(diphenylmethyl)piperazine
  • 1-(4-hydroxy-3-methylnaphthalen-1-yl)ethanone
  • 1-[4-(benzenesulfonyl)phenoxy]naphthalene
  • 1,4-Ethanonaphthalene,1,4,4a,5,6,8a-hexahydro-
  • 1-(4-Nitrobenzoyl)-4-piperidinecarboxylic acid