Corosolic acid

Suppliers

Names

[ Name ]:
Corosolic acid

[Synonym ]:
2-a-hydroxyursolic acid
hydroxyursolic acid
Corosolic acid
Urs-12-en-28-oic acid, 2,3-dihydroxy-, (2α,3β)-
2,3-dihydroxyurs-12-en-28-oic acid
2alpha-hydroxyursolic acid
2α-Hydroxyursolic acid
MFCD03840521
(2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
573.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₄₈O₄

[ Molecular Weight ]:
472.700

[ Flash Point ]:
314.6±26.6 °C

[ Exact Mass ]:
472.355255

[ PSA ]:
77.76000

[ LogP ]:
7.82

[ Vapour Pressure ]:
0.0±3.6 mmHg at 25°C

[ Index of Refraction ]:
1.567

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

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Precursor & DownStream

Precursor

2,3-O-Diacetylcorosolic acid
Ursonic acid benzyl ester
benzyl (1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
benzyl (1S,2R,4aS,6aS,6bR,8aR,12aR,12bR,14bS)-10-acetoxy-1,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,12,12a,12b,13,14b-hexadecahydropicene-4a(2H)-carboxylate
Ursolic Acid
Methyl corosolate
2-O-Acetylcorosolic acid
2,3-BIS(ACETYLOXY)-(2ALPHA,3BETA)-URS-12-EN-28-OIC ACID METHYL ESTER

DownStream

Articles

Nanoparticles Containing Curcumin Useful for Suppressing Macrophages In Vivo in Mice.

PLoS ONE 10 , e0137207, (2015)

To explore a novel method using liposomes to suppress macrophages, we screened food constituents through cell culture assays. Curcumin was one of the strongest compounds exhibiting suppressive effects...

Simultaneous determination of five triterpene acids in rat plasma by liquid chromatography-mass spectrometry and its application in pharmacokinetic study after oral administration of Folium Eriobotryae effective fraction.

Biomed. Chromatogr. 29 , 1791-7, (2015)

Folium Eriobotryae effective fraction (FEA), the extract of Folium Eriobotryae, had been used as anti-hyperglycemia and anti-hyperlipemia medicine in China. A previous study indicated that euscaphic a...

Corosolic Acid Inhibits Hepatocellular Carcinoma Cell Migration by Targeting the VEGFR2/Src/FAK Pathway.

PLoS ONE 10 , e0126725, (2015)

Inhibition of VEGFR2 activity has been proposed as an important strategy for the clinical treatment of hepatocellular carcinoma (HCC). In this study, we identified corosolic acid (CA), which exists in...