p-toluenesulfonyl fluoride

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Names

[ CAS No. ]:
455-16-3

[ Name ]:
p-toluenesulfonyl fluoride

[Synonym ]:
p-toluenesulfonyl fluoride
Benzenesulfonyl fluoride, 4-methyl-
4-Methylbenzenesulfonyl fluoride
MFCD00007421
EINECS 207-238-6

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
233.0±0.0 °C at 760 mmHg

[ Melting Point ]:
41-42 °C(lit.)

[ Molecular Formula ]:
C7H7FO2S

[ Molecular Weight ]:
174.193

[ Flash Point ]:
105.6±0.0 °C

[ Exact Mass ]:
174.015076

[ PSA ]:
42.52000

[ LogP ]:
2.74

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.503

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT8050000
CHEMICAL NAME :
p-Toluenesulfonyl fluoride
CAS REGISTRY NUMBER :
455-16-3
BEILSTEIN REFERENCE NO. :
2208423
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H7-F-O2-S
MOLECULAR WEIGHT :
174.20
WISWESSER LINE NOTATION :
WSFR D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,1,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 173,33,1954

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302 + H312 + H332-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R20/21/22;R34

[ Safety Phrases ]:
S22-S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
XT8050000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Precursor & DownStream

Precursor

  • para-Tolyl disulfide
  • 4-Methylbenzenesulfonothioic acid S-(4-methylphenyl) ester
  • P-toluenethiol
  • Tosyl chloride
  • Tetrabutylphosphonium chloride
  • p-Toluenesulfonic acid
  • 4-Toluenesulfonamide
  • Toluene
  • Sodium toluene-4-sulphinate
  • Fluorosulfuric acid

DownStream

  • Isocyano(phenyl)methyl 4-methylphenyl sulfone
  • Tosyl chloride
  • p-Toluenesulfonic acid
  • Benzene,1-methyl-4-(phenylsulfonyl)-
  • P-TOLUENESULFONIC ACID N-OCTYL ESTER
  • 1-Methyl-4-(methylsulfonyl)benzene
  • p-Tolyl (Trimethylsilyl)methyl Sulfone
  • Bis-(toluene-4-sulfonyl)-methane
  • Methyl 4-methylbenzenesulfinate
  • Sodium p-toluenesulfonate

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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Related Compounds

  • p-Toluenesulfonyl fluoride, alpha-bromo-
  • p-toluenesulfonyl fluoride,2-chloro-|A-(2-chloro-4-nitrophenoxy)
  • p-Toluenesulfonyl acetone hydrazone
  • p-Toluenesulfonyl isocyanate
  • o-Toluenesulfonyl fluoride
  • 2-benzothiazolyl-N-(p-toluenesulfonyl)-sulfinimidoyl fluoride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-cyclopropyl-3-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]propanoic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1-(1-Ethylpiperidin-4-yl)-2-methylpiperazine
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine