Adenosine 5′-monophosphate disodium salt

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Names

[ CAS No. ]:
4578-31-8

[ Name ]:
Adenosine 5′-monophosphate disodium salt

[Synonym ]:
Disodium 5'-O-phosphonatoadenosine
Disodium adenosine 5'-phosphate
Adenosine 5'-monophosphate disodium salt
MFCD00065023
Adenosine-5'-monophosphate disodium salt
Dinatrium-9-(5-O-phosphonato-β-D-ribofuranosyl)-9H-purin-6-amin
Adenosine 5′-monophosphate sodium salt
AMP disodium salt
EINECS 224-961-2
5'-Adenylic acid, sodium salt (1:2)
5'-AMP-Na2
Adenosine 5’-Monophosphate Disodium Salt
5′-AMP-Na2
Disodium [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl phosphate

Chemical & Physical Properties

[ Boiling Point ]:
798.5ºC at 760 mmHg

[ Melting Point ]:
232-235ºC

[ Molecular Formula ]:
C10H12N5Na2O7P

[ Molecular Weight ]:
391.185

[ Flash Point ]:
436.7ºC

[ Exact Mass ]:
391.026978

[ PSA ]:
201.54000

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7481600
CHEMICAL NAME :
5'-Adenylic acid, disodium salt
CAS REGISTRY NUMBER :
4578-31-8
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H12-N5-O7-P.2Na
MOLECULAR WEIGHT :
391.22
WISWESSER LINE NOTATION :
T56 BM DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPO&O&O &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
830 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression Lungs, Thorax, or Respiration - other changes
REFERENCE :
TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 33,24,1974

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AU7481600

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Adenosine

DownStream

  • D-RIBULOSE 5-PHOSPHATE DISODIUM SALT
  • 5'-Adenylic acid
  • 5'-UMP disodium salt

Articles

Regulation of AMPK by the ubiquitin proteasome system.

Am. J. Pathol. 178 , 4-11, (2011)

The 5'-AMP-activated protein kinase (AMPK) functions as a metabolic fuel gauge that is activated in response to environmental stressors to restore cellular energy balance. In the heart, AMPK coordinat...

New strategies in prostate cancer: targeting lipogenic pathways and the energy sensor AMPK.

Clin. Cancer Res. 16 , 3322-3328, (2010)

Although the role of metabolic syndrome (MS) and a high fat diet in prostate cancer (PCa) risk is still a matter of intense debate, it is becoming increasingly clear that obesity can cause perturbatio...

Identification of a novel CaMKK substrate.

Biochem. Biophys. Res. Commun. 410 , 45-51, (2011)

Ca(2+)/calmodulin-dependent protein kinase kinase (CaMKK) phosphorylates and activates specific downstream protein kinases including CaMKI, CaMKIV and 5'-AMP-activated protein kinase. In order to exam...


More Articles

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